Board Thread:Theories and Speculation/@comment-995176-20170417010515/@comment-734582-20170417161425

Kakashisologod1 wrote: So if they do become,boruto will have slug,sarada will have snake and mitsuki will have a frog o_O,pretty intresting. I don't know, they could play it straight. They might not go down the Sage route at all. What is clear however is that though the connections to the other sannin exists and the setup is similar, there are also numerous and major differences. So whatever happens next will be significantly different from what came before.

I can even see them splitting off into Clan heritage: Sarada as the Lone Uchiha, Sannin who uses powerful dojutsu. Mitsuki the Snake Sage. Boruto as the inheritor of the Otsutuski/Hyuga branch.