Board Thread:Theories and Speculation/@comment-3568954-20141031085827/@comment-1210805-20141031094608

Actionmanrandell wrote: TheUltimate3 wrote: Kishimoto decided that Creation Rebirth shortening her life is what is making her look old, to show that her lifespan is short. And we have no idea how much she used it during her time outside of Konoha? Or hell during the war.

never once have they said in the manga or in any interviews that creation rebirth makes her look older than she does

Omega64 wrote: That's not how hayflick is supposed to work. First off, you should know that hayflick is a theory, not biological fact. The theory behind it is that skins cells lose elasticity as the body ages, caused by the cells shortening division. They all don't stop dividing at once. Tsunade wouldn't just die, she would grow old much earlier and die much earlier, she wouldn't just plop dead. Also, her being a Sannin has nothing to do with it, perhaps her Uzumaki lineage increases her overall age, but even Mito was seen to be extremely old at the time of her death. We have no idea how abused Tsunade's body has become because of Creation Rebirth.

If you want to create a speculation forum that's fine. But don't spend the entire time shooting down theories. Just a little piece of advice. </ its not about shooting you down its about discussing it. No, but it has blatantly said that it accelerates the duplication of her cells and in turn, shortens her lifespan. It's pretty clear that Kishi's intent is to say that that increased cell division makes speeds up her aging.