Board Thread:Theories and Speculation/@comment-32369776-20170708034118/@comment-734582-20170709153152

Bambusek wrote: Well, from all the Senjus and Senju related characters very few had any importance: Kushina and Naruto aren't senju.

It's still pretty much the most important clan. Hashirama and Tobirama by themselves logged enough achievements for the entire clan, what with essentially creating the modern shinobi world and it's rules and institutions. Only the Uchiha, as far as i can recall, had more influence on the plot and that wasn't good influence. Bambusek wrote: The rest weren't important enough to came up with explanation why they died off They didn't all die off. Given that Tsunade is the granddaughter of a Senju, if there was some mass-dying or eradication of Senju, she'd at least have mentioned something. The Uchiha massacre was referenced a few times, while the Uzumaki massacre was not really mentioned until Kushina told Naruto, because of all the secrecy. But we've seen several Senju in the plot and and no point was there are reference to some mass dying.