Board Thread:Naruto Discussions/@comment-24347194-20150211225344/@comment-5936871-20150406173552

The difference is Itachi was never known for his skill in body flicker nor was he known for his physical prowess in taijutsu and his speed. So in comparison to Minato, he couldn't keep up with him in regular physical combat. As for the rest, that may be true but we still don't know how strong he would have been if he wasn't sick. This is about how strong both of them were before they died, so that includes Itachi's sickness as well. In the end, since Itachi is sick, I believe Minato would win.