Kara

is a secret society founded by Isshiki Ōtsutsuki.

The group is made up of and, with each of the Inners being in charge of a particular region. Each Inner appears to bear a facial tattoo of a Roman numeral and wears a black hooded cloak with coloured lining, fastened at the right shoulder with a metal pin; all Inners are regarded as completely monstrous in power.

Outers are individuals who assist Kara from the outside to complete missions requested by the Inners, acting as conspirators, sleeper agents, and spies. Members include politicians and merchants, some of whom actively work to undermine the rule of the Daimyō and Kage. Outers are also partly responsible for the widespread development and proliferation of Scientific Ninja Tools; as the Outers include engineers and scientists from various villages, they are able to significantly develop and improve the tools before bringing them back to Kara, leading to them possessing the latest in technology and engineering.

The secret society has accumulated a great deal of wealth and political influence, makes use of Scientific Ninja Tools, and communicates over long range via genjutsu.

History
When Isshiki Ōtsutsuki came to earth over one thousand years ago to cultivate a chakra fruit, he was betrayed by his lower-ranked comrade, Kaguya, who injured him to the point of near death. Desperately clinging to life, Isshiki parasitically invaded Jigen, who was the only available human at the time.

Using Jigen as a host body, Isshiki formed the secret society, Kara, which recruited a group of people — the Inners — to assist him in cultivating a new God Tree to collect its chakra fruit, under the promise that their personal wishes would be fulfilled. Amado, the chief scientist of the organisation, modified every member with advanced Shinobi-Ware that they had an unwitting Katasuke Tōno deliver to them.

Due to losing Kaguya, Isshiki intended to feed himself to the Ten-Tails to have it bloom into the God Tree, as there were no other Ōtsutsuki to sacrifice. However, with his body being so critically and irreparably damaged by Kaguya and his vessel of Jigen being incompatible with the Kāma, this would produce an inferior Chakra Fruit. In addition, Isshiki began preparing a new vessel to continue his survival, having purchased fifteen children to carry out his experiments to ensure his next body would be suitable for a full lifetime, with Kawaki being the result. Kawaki's development, along with the God Tree's cultivation, became factors that had Kara pressed for time in their goals.

However, when Boruto Uzumaki became the vessel for Momoshiki Ōtsutsuki, the time limit was very well relaxed. Kara, therefore, shifted their plans to feeding Boruto to the beast instead, as his healthier and stronger body along with being compatible with the Kāma would result in a more potent Chakra Fruit.

Inners

 * Isshiki Ōtsutsuki, the leader of Kara and an ancient Ōtsutsuki who originally came to Earth with Kaguya Ōtsutsuki. His current goal is to restore himself via his Kāma and a suitable new host body.
 * Jigen, the former vessel for the de-facto leader of the organisation. He had the Roman numeral "Ⅳ" tattooed under his left eye. He was killed by Koji, leading to Isshiki's resurrection through Jigen's corpse.
 * Delta, a woman with long, curly hair and prosthetic eyes. She has a tattoo of the Roman numeral "Ⅰ" in the centre of her forehead.
 * Code, a cocky young man with dishevelled hair and a craniofacial prosthetic who has the Roman numeral "Ⅵ" under his right eye.

Inners

 * Deepa, a tall pale man with the Roman numeral "Ⅶ" below his eyes. He was defeated by Boruto, Sarada, and Mitsuki, and what remains of his corpse was retrieved by Victor. Deepa was noted to be untrustworthy by Kara. (Anime only)
 * Victor, a short, stocky, elderly man with an eye-patch over his right eye and a prosthetic right leg. He had a tattoo of the Roman numeral "Ⅴ" on his left temple, and was known for his regeneration technique. In the anime, Deepa implies he gained his position due to a large investment from his medical care manufacturing company. He was burned to death by Koji Kashin.
 * Boro, a giant, gregarious man with a beard and moustache. He had a trio of tattoos on his face that appear to form the Roman numeral "Ⅲ". He was killed by Boruto's Rasengan.
 * Koji Kashin, a genetic clone created from the DNA samples of Jiraiya, whose sole goal is to eliminate Isshiki. He was an Inner prior to his defection, in charge of the Land of Fire sector. He has lines under his eyes that appear to form the Roman numeral "Ⅱ".
 * Amado, a genius scientist that served as Jigen's right hand and the head of the organisation's research and development division. He developed advanced Shinobi-Ware for Kara and is responsible for the creation of all its . Under Jigen, he was never granted leave, and is thought to know everything about the organisation. He has since formally defected to Konohagakure. He was an Inner prior to his defection.

Outers

 * Garashi Tōno, an orphaned civilian from Amegakure who believes in Kara's ideals. Despite his absolute loyalty to the organisation, Garashi was used simply to ensure no one knew of their work in the village, thus sacrificing him in the process. (Anime only)
 * Iwa Doctor, the doctor who worked with the retired Third Tsuchikage Ōnoki, to create the Fabrications and Akuta. He later went to work for Victor's company in the Land of Valleys. He was left to be consumed by Victor's artificial God Tree. (Anime only)
 * Victor's Secretary, who works at Victor’s company in the Land of Valleys. She was killed by Orochimaru. (Anime only)
 * Ao, a war veteran from Kirigakure. He was killed by Koji's Boiler Toad summon after pushing Boruto away from harm.
 * Garō, an associate of Delta who had prior interaction with Kawaki and was killed by him after a short fight.

Trivia

 * The kanji used for the two divisions of the organisation are and, respectively referring to the sanctum and the nave of a Heian-style Buddhist temple. When broken into individual kanji, they can be read literally as "inner team" and "outer team".
 * While not a member, Kawaki has a Roman numeral Ⅸ tattoo, which is located under his left eye.
 * Additionally, while viewed by Kara as just the vessel, Kawaki apparently held some access to Kara's information, as he noted that he had read Kara's files to learn about Tailed Beasts.
 * While Katasuke Tōno was never a direct member and was placed under genjutsu by a Kara agent, this made him act on the group's objectives which revolved around the development of scientific ninja tools and industrial espionage.