Fusō

was a nurse and a citizen of Amegakure, where she lived in a small village with her son and husband.

Background
During the Second Shinobi World War, Fusō and her husband Ise were providing humanitarian aid. One night during the war, Fusō and her family were hiding in their battle-damaged house when Konoha ninja broke in looking for food. Fusō and her family tried to sneak away but when they were detected she and Ise brough the attention to themselves to give Nagato a chance to escape. The Konoha ninja, assuming the couple were enemy ninja, attacked and quickly killed both of them.

Witnessing this, Nagato unknowingly awakened his Rinnegan, and he subsequently killed the two Konoha-nin. Nagato buried his parents before leaving to search for food. The death of his parents is the first great tragedy of his life, and in his eyes evidence that the peace Konoha preaches comes at the cost of others' lives.

Personality
As a nurse, working alongside her husband to give aid to others in times of war, Fusō was a very compassionate woman. She loved her son very much, willing to sacrifice her own life to allow Nagato to escape.

Trivia

 * Based on Obito's words, at least one of them is descended from the Uzumaki clan. A common trait of the clan is red hair. While it is unknown if either of Nagato's parents has red hair in the manga, in the anime, Fusō's hair is red.
 * Fuso and Ise are both named after Japanese ships.