Board Thread:Versus Debates/@comment-9782468-20160419063438/@comment-28300173-20160425091157

Itachi is surely a masterclass shinobi... I mean, he's a real natural. He wouldn't go down easy. I'm talking, had the Uchiha Massacre been avoided, I say that Itachi would have been the Fifth Hokage and the first Uchiha to do so.

That said, Kakashi is a true prodigy himself, and Guy is likely (barring a future version of Lee) the greatest single virtuoso of taijutsu in ninjacraft history.

Combine Kakashi's knowledge, elemental skill, and overall well-roundedness and Guy throwing himself into the 5th (or higher) gates, I think that would be a deadly situation for Itachi, In the story, I believe he would retreat. In a death battle, I think they would win.