Board Thread:Theories and Speculation/@comment-29332822-20170122212627/@comment-6225479-20170214092441

If you allow the annihilation of the uchia clan to be the one thing all future events hinge on, then yes it is possible. However Obito would still be a likely contender as he is out side of this little pocket and would still be subject to his full story line.

Yet, the pragmatic realist in me says, that things still would have happened to both Itachi and Sasuke that would have led them to wanting to be stronger.

Looking at Kakashi and his short stent in Anbu, I doubt even without Danzo, that Itachi would have come through all of that unscathed.