Board Thread:Theories and Speculation/@comment-26260713-20160303045832/@comment-27120402-20160303051507

Being that you're writing a fanwork, it's really up to you and you can take anything we say with a grain of salt, but if you were to take the most canon iteration of Sasuke and place him within your story, it probably wouldn't play out like that. Sasuke lived a life of great loneliness, perhaps feeling even more isolated than Naruto. Unlike Naruto, Sasuke suffers from a degree of post-traumatic stress as well, which causes him to be unable to properly assess and deal with his own emotions.

It's unlikely Sasuke would have any sort of relationship with the Hyuga clan. Neji and Sasuke canonically used each other as benchmarks for their own ability, being that they were both considered prodigies, but had no real relationship.