Board Thread:Consensus Track/@comment-38502514-20190216075013/@comment-28908658-20190218225629

"Biologically, nothing states that Orochimaru has been changed to female or a combination of male or female."

Exactly. And the same can be said about pretty much every questionable character. We don't know what their DNA is, or which ones even have DNA, or what their private anatomy looks like.

We just know that some of them are presented as male, and some of them are presented as female.