Board Thread:Theories and Speculation/@comment-34656247-20180531072459/@comment-26636534-20180602155149

Tsukuyomi's power is not that it can't be broken. Tsukuyomi is a powerful genjutsu, but users here in favor of it seem to forget what makes it truly powerful. Tsukuyomi's greatest strength is it's ability to alter the victim's perception of time. That is, making one second seem like three days. Along with it's relative speed and lack of needed hand signs, make it quite a formidable jutsu.

Now, when used on Kakashi, it caused Kakashi to experience three days of torture. Mental torture that his body could not handle. When used on Sasuke (the second time), Itachi did not apply any time dilation to it. Thus, removing the main power to this genjutsu, since he wasn't actually trying to kill Sasuke.

What do we know of Hashirama? Hashirama grew up in the warring states period, fighting Uchiha for decades. It is not speculation to say that he encountered Uchiha genjutsu. A realistic assumption would be to say that sharingan: genjutsu is not effective against him. We also know he is a transmigrant and he has hax abilities of, wood release, healing, SM, enormous amounts of chakra.

Hashirama's cells have the unique ability to enhance the abilities of others, MS abilities in particular as seen by Obito, Madara, Danzo and even others such as Orochimaru. It is clear that Hashirama is the exception to many so called 'rules' that apply to regular shinobi.

So, would Tsukuyomi work on Hashirama?

Since no shinobi has ever simply blocked sharingan genjutsu, Tsukuyomi can be cast on Hashirama.

Will it be effective against Hashirama?

At minimum, Hashirama can endure three days of torture. He could push through relatively unscathed. At his best, and from what we know about his cell's ability to enhance other abilities, his chakra levels, his experience fighting powerful Uchiha's, Hashirama should not be affected by the genjutsu.

Can Hashirama break Tsukuyomi?

It depends on speed really, if time dilation is applied then I don't think so. If no time dilation is applied then yes.