Board Thread:Boruto: Naruto the Movie/@comment-26665178-20150722194758/@comment-26369387-20150811181055

Well, Orochimaru certainly had more feminine look in Gaiden...My theory: Orochimaru decided to change into "Orochiko" and have a child(Mitsuki) out of scientific curiosity. As for how... Artificial insemination?

True, he has already been in female body before, but that was when Orochimaru was seeking immortality. This time he's "she", because "she" has finally learned the lesson "passing your will to next generation".

Just a little theory of mine...