Board Thread:Versus Debates/@comment-27418151-20160521030355/@comment-734582-20160521153101

Legendary Super Saiya-Jin 4 wrote: Tobirama Senju will win for sure imho. Amaterasu and Kagutsuchi requires a brief charging period, which is enough time for Tobirama to create Shadow Clones and use Water Release: Exploding Water Colliding Wave Doubtful. People with rinnegan have detected the buildup of chakra in the eye in order to counter it, but other than that there's barely any noticeable effect. In this battle, Amaterasu is far more powerful as a defensive than an offensive jutsu. It either limits his movements to more predictive ways, destroys Hiraishin markings to limit that jutsu, or it plain destroys water jutsu. It would inevitably force Tobirama to deal with the flames.

Especially Tobirama's water release is problematic for him, since the heat of Amaterasu and tobirama's water would easily prepare Kirin, which cannot be evaded.

It would inevitably come down to the problem that Tobirama would have to hit Sasuke, and Sasuke can always defend himself with Amaterasu and Susanoo. Stamina is no issue here: Itachi could form the ribcage in the time Sasuke fired Kirin, so he can always flicker it on and off as needed. MS Sasuke was testing the limits of Susanoo, but EMS Sasuke was clearly wiser and more restrained in it's use.

I think it comes down to how much prior knowledge the two have of each other. In a limited information case, Hiraishin's secrets are more powerful than Mangekyou's. (Since nobody realistically thinks highly of a marked kunai, whereas special eyes go all the way back to the Sage of Six Paths himself).