Board Thread:Versus Debates/@comment-1872728-20170911101125/@comment-30323490-20170911124315

Hashirama has crazy regeneration, and the toughest thing Jiraya or Minato could hit him with would be the rasengan, which most likely won't do the job. Their best bet would be for Naruto to attempt to land a rasenshuriken on him, and hope his chakra network gets cut out.