Sakura Haruno

is one of the main characters in the series. She is a chūnin-level kunoichi of Konohagakure, a talented medical-nin, and a member of Team Kakashi.

Background
During her early years in the Academy, Sakura was frequently bullied by others due to her large forehead. To try and combat this, Sakura used her bangs to hide her forehead, fuelling the other kids' teasing by indicating she was sensitive about it. Ino Yamanaka, realising this, helped Sakura by giving her a red ribbon that she used as a way of drawing attention to the cuter features of her forehead, which helped Sakura overcome her insecurity. The two became best friends and Sakura grew more confident, developing her own unique personality under Ino's guidance. In the anime, one day about five years ago while searching for Ino to have lunch with, she spots her, along with Shikamaru Nara and Chōji Akimichi stealing bits of food from others. Curious as to what they are doing, she follows them, discovering that they are bringing the food to a mysterious young child named Yota. Later, despite her genuine appreciation of for Ino's friendship, Sakura felt that she was living in Ino's shadow and longed to prove herself as Ino's equal. Later, when Sakura found out that Ino also had a crush on Sasuke Uchiha, Sakura ended their friendship so that they could compete for Sasuke's love, thus beginning a bitter rivalry between the two.

Personality
As a child, Sakura lacked self-confidence and was highly self-conscious about her large forehead. As such, she would cover her forehead with her bangs. It was not until she met Ino Yamanaka who would later defend her against her bullies and tell her that if she hid her forehead, it would only make it stand out more. It was after this that the two became inseparable friends and Sakura started to become more bold and self-confident. As a student, Sakura was noted to be an honour student, and even to this day, Sakura's scholastic intelligence is hardly rivalled by any of her peers. Despite this, however, as a teenage girl, Sakura became more interested in her looks as opposed to practising her ninja skills, something that she was scolded for occasionally. As such, she became a selfish individual and even developed a rivalry with her best friend Ino, referring to her as "Ino-pig".

In Part I, Sakura was self-centred, arrogant, vain and was solely focused on herself and developing a relationship with Sasuke Uchiha. Due to this, Naruto's advances and attempts to gain her attention as well as his antics would generally irk her as she saw them as nothing more than childish and foolish. Sasuke pointed out that because Sakura had not experience loss in her life, she could not understand Naruto nor him, prompting Sakura to start looking at things from Naruto's perspective in an attempt to understand her team-mate. This caused them to develop a deep and mutual friendship which endured even when Naruto had left the village for two years. In Part II, Sakura becomes more mature and less self-centred, though she still has a bad habit of being hyper critical, specifically with Naruto. When she learns of the various hardships Naruto faced with the Nine-Tails and Akatsuki. Saddened by the impact both forces have had on his life, Sakura becomes protective of Naruto and tries to do whatever she can to help him overcome these obstacles and eventually, due to there time spent together as Team 7, develop a deep friendship, though Naruto's romantic feelings towards Sakura remains un-reciprocated.

Sakura is well known for being very stubborn, impatient and very hot-tempered, which causes her to lash out at others in violent rages, verbally and physically (the victim typically being Naruto and at times Sai), which is a recurring theme of her character. Minato noted her short temper reminds him of Kushina.

Nevertheless, Sakura is also strong-willed, determined, and courageous, witnessed during the Chūnin Exams when her team-mates were incapacitated and it was left up to her to defend her team-mates from Team Dosu. This was also witnessed through her spurring Sasuke on to act when they were confronted by a disguised Orochimaru. Not one to lose or give up in a fight, when it came down to it, held captive by her hair which Kin Tsuchi mocked for being lustrous, she willingly cut her hair off and then confronted Zaku Abumi head on, despite her disadvantage. This was also prominently seen during her fight with Sasori where despite being told to run by Chiyo, she stayed and fought, noting that she had inherited her master's contempt for losing.

At the start of the series, Sakura had a deep infatuation for Sasuke Uchiha, rooted in his good looks, cunning, cool attitude, and prodigious talents. For that reason, many of Sakura's early appearances were dedicated to her continuing efforts to win his affection. As the story progressed, she began to recognise Sasuke as a real person with imperfections, and developed a more sincere desire to be there for him, and later fell in love with him. Sakura also became concerned that Sasuke would someday abandon her and the rest of Konoha in his quest for power. When her fears came true at the end of Part I, Sakura did all that she could to stop Sasuke from leaving, such as professing her love for him and even offering to join him. Despite thanking her and sounding grateful, Sasuke knocked Sakura unconscious and left the village.

Despite the fact that she cursed her own uselessness at first, she decided to later take matters into her own hands and help Naruto to being Sasuke back home. Although she still worries about his well-being, Sakura is willing to attack him if it means returning him to Konoha, however, as time went on and Sasuke became an increasingly more dangerous criminal, Sakura recognised that Sasuke must be stopped at all costs. Despite agreeing that they had no choice but to kill Sasuke themselves to prevent Konoha from being involved in a war by his criminal actions or his death at a foreign country's hand, Sakura was immensely saddened and distraught at the notion nonetheless to the point where it drove her into trying to take care of the Sasuke situation by herself. Even going as far as to have Naruto abandon his effort to save Sasuke when she realised how much suffering it had brought to Naruto.

Ultimately, while still in love with Sasuke, Sakura has decided that the only option left for her is to have faith in both Naruto and Sasuke.

Inner Sakura
Another detail of Sakura's personality is her brashness. In Part I, these were turned inwardly, in the form of — a manifestation of her inner emotions. In addition to comic relief, Inner Sakura represents Sakura's actual opinion on things when she outwardly remains clam, collected, or reserved. Inner Sakura's appearances are typically marked by an exclamation of — a phrase which has no literal meaning, but is usually translated as "Hell yeah!", "Hell no!", or "Damn it!", depending on the situation. The English anime, for censorship reasons, replaced the aforementioned phrases with a forceful "Cha!". Inner Sakura is unique as it is in a way a second will within Sakura's mind. When Ino used the Mind Body Switch Technique on her, Inner Sakura was able to repel the user from her body, suggesting that Sakura has a split personality, consisting of the "Inner Sakura" and her normal personality.

Although she appears quite frequently at the start of the series, after her apprenticeship started with Tsunade, and Sakura began to subconsciously adopt some of her master's mannerisms, these feelings would actually manifest through Sakura herself, in violent outbursts that would result in Naruto usually being hit for his foolish, or perverted actions. Despite this, however, Inner Sakura will still manifest in some cases such as when Naruto mouthed off to Tsunade. She disciplined him before Tsunade could, noting how fearsome Tsunade could be in cases such as those. Minato Namikaze noted how Sakura is eerily similar to Kushina after Sakura headbutted Naruto.

Appearance
Sakura has bright pink hair, large green eyes, and fair skin. Sakura was often bullied due to her rather large forehead hence her nickname of "Billboard Brow", due to this she wore her bangs over her forehead in an attempt to cover it, though Ino encouraged her to wear her hair back. In Part I, Sakura wore a red qipao dress with white circular designs, with or without short sleeves, with a zipper, tight dark green shorts, and a forehead protector which she used to accentuate her face.

In Part II, Sakura, now a chūnin, has donned a new attire consisting of a red top with the same design as the upper-half of her Part I outfit, with black gloves, black boots, black shorts, short pink apron skirt, and pink elbow protectors and forehead protector which is now on a red cloth. Her skirt and elbow protectors are also pink in the anime. Sakura is now also armed with a tantō which she wears above her medical pouch. When she's not on a mission, she wears her regular red shirt, with a light yellow shirt under it, and a navy-coloured skirt. In this outfit, she still wears her boots. She later dons the uniform of the Allied Shinobi Forces inclusive of a Konohagakure flak jacket, albeit opting to wear a skirt instead of pants and her regular boots. She later changes her skirt to pants to assist the medic unit.

Another notable trait of Sakura's appearance is her hair. At the series' beginning, Sakura's hair was very long (when she was young, there was a rumour that Sasuke was attracted to girls with long hair). After Sakura began to protect the unconscious bodies of Sasuke and Naruto after their battle with Orochimaru, Kin Tsuchi grabbed Sakura's hair and taunted her for paying more attention to her appearance than practising her technique. Kin kept Sakura captive, holding her tightly by the hair and forcing her to watch Zaku Abumi attack Lee. This caused Sakura to cut her hair to release Kin's hold on her, and determinedly attacking Team Dosu with a new goal of surpassing her team-mates. Her hair was very short and messy that time. After the battle, Ino cuts Sakura's hair to make it neater. During the time she trained with Tsunade after the Chūnin Exams, she had let her hair grow back but has since then cut it again in favour of her new, shoulder-length hairstyle. Like Shizune, she also has the tendency to pin her hair up in a ponytail when working.

Abilities
At the start of the series, Sakura's abilities as a ninja were considerably less than those of her team-mates; Sasuke and Naruto, with her greatest strength being her intelligence. After two-and-a-half years of training with Tsunade however, Sakura's abilities greatly increased to the point that she could hold her own against powerful enemies such as Sasori. Her skills in other areas have also increased, such as being able to locate Kakashi during the second bell test — something Naruto could not do — as well as tricking Sai, Kiba, and Lee into fighting each other so that she put them all to sleep. Along with physical abilities, Sakura has also inherited her master's resilience and contempt for losing. This was best displayed after she had been surrounded by a cloud of poison, and used an explosive tag to dispel the cloud of smoke without sustaining much damage herself.

Due to her excellent chakra control, Sakura has been noted to have a natural aptitude for genjutsu, though thus far she has only been seen dispelling genjutsu. She was amongst the few elite shinobi who successfully detected, and dispelled Kabuto's sleep-inducing genjutsu and helped Naruto out of it. She was also able to decipher at the start of the Chūnin Exams that they were trapped in a surrounding-altering genjutsu. It does seem, however, that she has put these skill towards medical ninjutsu instead.

Chakra Control
Soon after the start of their first mission, Sakura discovered that she had an excellent control over her chakra, and as such she had an innate ability to use techniques to their maximum efficiency without wasting any chakra. Kakashi pointed out that her ability to gather chakra from every part of the body and then using it with great timing made her superior to her team-mates in that respect. While this particular ability was never put to great use in Part I, her chakra control became a focal point of Sakura's fighting style and medical abilities in Part II. In Part II of the anime, with her excellent chakra control, she was chosen in sealing the Three-Tails with the Four-Corner Sealing Barrier along with Shizune, Ino and Hinata.

Medical Ninjutsu
Sakura's naturally refined control of her chakra had been taken to new heights over the time skip, an ability utilised to its fullest by the training she had done with Tsunade. With her excellent chakra control, Sakura had turned into an excellent combat medical-nin, and had shown herself to be able to heal fatal injuries with relatively little effort, even when more experienced medics would deem it a lost cause. She also has shown extensive knowledge of poisons having been taught by her senior pupil Shizune — learning how to imbue weapons such as kunai, with poison. She also has an extensive knowledge of herbal medicines, surpassing even the knowledge of Chiyo as well as other chemicals such as powerful sleeping gases taught to her by Tsunade. Her knowledge was great enough to withdraw Sasori's advanced poison directly from Kankurō's body, and use that as a base template to create multiple antidotes swiftly afterwards. During her fight with Sasori, she was able to start healing herself even with a poisoned sword still lodged in her abdomen.

At the end of Part I when Tsunade observed Sakura successfully heal a fish with the Mystical Palm Technique, Tsunade remarked that Sakura had come so far, and she hadn't seen such talent since Shizune. Sakura can also assist with autopsies, as seen when she and Shizune performed an autopsy on a White Zetsu during the Fourth Shinobi World War, and she has knowledge of cells and DNA. A few individuals have even commented that Sakura has the potential to one day rival Tsunade in terms of medical skill, and perhaps even surpass her given enough time, though Sakura has stated that Tsunade's skills are far greater than her own.

Taijutsu
Although not known for her strength in Part I, Sakura was still strong enough to knock Ino several metres backwards with only a single strike during their match in the Chūnin Exams. In the anime, during a mission to the Land of Tea, she was seen breaking off the mast of a ship and using the large log of wood as a weapon.

In Part II, Sakura's taijutsu skills have seen tremendous growth thanks to Tsunade's training. By building up and releasing her chakra with precise timing, Sakura can easily demolish or destroy obstacle with powerful punches or kicks. An opponent struck by her full strength could suffer blunt force trauma resulting in broken bones, ruptured organs, or even death. She was even able to knock her opponent's head clean off. Through repeated use, Sakura no longer needs to put any conscious effort into using this strength, and so can use it instantly. Her strength, coupled with her medical expertise and the beauty she gained over the time skip, had caused many to see Sakura as a younger version of Tsunade, or even someone who could even surpass Tsunade. She was also able to use this new-found strength to lift a boulder nearly twice her size, throw the Lion-Headed Kannon with enough force and speed that it caught Sasori by surprise, and was also able to stop an airborne Sasori from reaching his target, later smashing his body to pieces. During her battle with Sasori, Sakura's strength was enough to knock away the giant constructs created by the Iron Sand Gathering Assault technique. Sakura's strength was great enough to completely immobilise a transformed White Zetsu Army clone, which are extremely durable, with just one blow.

Another key component of Sakura's fighting style is her evasive skill. As a field medic, she cannot afford to be gravely injured or killed on the battle field, as drilled into her by Tsunade when she trained her. Sakura would attempt to read an opponent's fighting style in order to find the dominant hand/foot or anything that the enemy was using. With that, she could increase her evasive skill to impressive levels. Sakura was proficient enough in this that she could figure out Sasori's finger movements and predict the movements of his puppets. Her skill in evasion is so great that she can defeat one-hundred puppets without even being scratched. Although Chiyo aided Sakura in this occasion, she notes that Sakura hardly needed any help.

Intelligence
Sakura's original defining characteristic was her intelligence, as seen with her consistently high test scores while in the Academy. Sakura has a keen talent for observation and analysing, which she uses to overcome most forms of deception. Moreover, in the first phase of the Chūnin Exams, Sakura was able to answer all the questions on the paper test quickly, even though the examiner Ibiki Morino later commented that this feat could not be accomplished by a genin, hinting her exceptional knowledge and intelligence as a student. Sakura could also cleverly set traps, that could be triggered by herself to attack the opponent, and even use obvious traps as decoys to lead opponent's into other traps. In the Forest of Death, she tricked Zaku into thinking she was using the Body Replacement Technique. However, Sakura's focus on her studies in the Academy greatly affected her physical performance. Her poor combat skills and stamina prevented her from being helpful during the earlier battles in the series.

In Part II, along with her other attributes, Sakura's exceptional intelligence and keen observation skills also improved during her training with Tsunade, who taught her to read and decipher the attack patterns of her enemies and act accordingly. As a result, she could now read complex patterns in her opponent's attacks, even opponents as strong as Sasori, a feat which even surprised an experienced war veteran like Chiyo. She had him to believe that the poison she received from him has affected her. When Sakura along with her team encountered Tobi and his technique, Sakura was able to assume its mechanism and deduce that Tobi was only pretending to be affected. Sakura is also shown to be skilled at planning, being able to formulate a plan to kill Sasuke by the use of a poison and prevent Kiba, Sai and Lee from following her by the use of a sleeping gas bomb. During the first night of the Fourth Shinobi World War had ended, when a spy had infiltrated the Logistical Support and Medical Division compound, Sakura was able to work out that the spy wasn't using the Transformation Technique as the sensors would've detected the spy. When having a talk with Neji, Sakura was able to deceive him and attack him while he was unprepared. She was able to extract information from the assassin and piece together the mechanics behind the enemy's abilities, using information she had come across previously, as well as what the clone told her.

Introduction Arc
Upon being assigned as a member of Team 7, Sakura spent much of her time trying to appeal to Sasuke, despite the fact that Sasuke had no interest in her and had a habit of belittling her. All the while, Naruto tried to appeal to Sakura, despite the fact that she had no interest in him and degraded him whenever given the opportunity. As such, when Kakashi administered a test on the three to see if they would be allowed to become genin, Sakura preoccupied herself with following Sasuke instead of helping Naruto.

After Kakashi lectured Sakura for this, as well as Naruto and Sasuke for their respective faults, Sakura realised that if they were to become genin, they would need to work as a team, even if that meant breaking the rules. This revelation having been the goal of the test, Kakashi passed the three, Team 7 being the first group to have ever passed his test.

Land of Waves Arc
Sakura accompanied the rest of her team on their first mission to the Land of Waves, to act as bodyguards for Tazuna. While there, Kakashi administers a Tree Climbing Practice, and Sakura masters the exercise on her first try. This leaves her in charge of escorting Tazuna while Naruto and Sasuke complete the training. When they are later attacked by Zabuza and Haku, Sakura protects Tazuna while Kakashi, Naruto, and Sasuke battle the enemy. After hearing that Sasuke was apparently killed, Sakura violated Shinobi Rule #25 of not showing any kind of emotions by crying for Sasuke's loss even as she recited it. When Sasuke turned out to have only been in a death-trance, Sakura was relieved that he was alive. Once their mission was completed, Team 7 returned to Konoha.

Chūnin Exam Arc
When Team 7 is entered into the Chūnin Exams, Sakura is reluctant to participate because she feels she is too weak. With some reassurance from Sasuke, she agrees to enter. During the first, written portion of the exam, Sakura is one of the few examinees that is able to answer the questions without cheating. She instead spends her time lamenting that Naruto is probably too stupid to answer the questions or know that he is supposed to cheat, and contemplates forfeiting so that he doesn't need to embarrass himself. After seeing Naruto's confidence in himself, she decides against it, and they pass the first phase.

Soon after the start of the second phase of the Chūnin Exams, Team 7 was attacked by Orochimaru. Although Naruto and Sasuke did their best to defeat Orochimaru, both were rendered unconscious, and Sakura was left to take care of them. When they were attacked by a group of Oto genin sent by Orochimaru to kill Sasuke, Sakura tried to defeat them with some traps she had pre-prepared, though the group easily avoided her efforts. Just as the Oto genin were about to turn their attention to Sakura, Rock Lee came to her rescue, determined to protect Sakura at all costs. Despite his efforts, Lee was defeated, and the Oto genin again turned their attention to Sakura. Kin Tsuchi immobilised Sakura by grabbing her hair, scolding her for putting more effort into her looks than her abilities as a ninja.

Distraught that people were always fighting for her because she couldn't fight for herself, Sakura resolved to better herself as a ninja. Cutting off her hair to release herself from Kin's grasp, Sakura began to form seals before she is impaled from behind by Kin's senbon. Sakura, however, is revealed to be a replacement. Bearing down on Zaku, Sakura launches a volley of kuai at him which are blasted back at her. The impaled Sakura turned out to also be a replacement, and as Zaku attacked her from above also believing that Sakura to be a clone, the real Sakura, while injured, is able to immobilse Zaku's arms: impaling one with a kunai and biting down on the other. This display spurred Ino and her team into coming to Sakura's aid, allowing her some rest. The unconscious Sasuke re-awakened after receiving Orochimaru's cursed seal, and immediately asked Sakura who injured her. Quickly overcome by his new cursed seal, he began a violent rampage on the Oto ninja who were present. Frightened by his new behaviour and after having realised that "this is not Sasuke", a tearful Sakura rushed to his side and embraced him, begging him to stop. Her words and embrace got through to him, and his cursed seal quickly receded.

In the preliminary matches of the exam, Sakura was pitted against Ino. After Sakura and Ino exchanged insults, Ino followed Sakura's earlier example and cut her hair, leading Sakura to believe that Ino had lost her mind. In actuality, Ino cut her hair to help her in battle; by sending chakra into her cut hair, Ino was able to tie Sakura in place, allowing her slow-moving Mind Body Switch Technique to have no difficulties in finding its target. After taking control of Sakura's body, Ino tried to force Sakura to forfeit, but thanks to Naruto's cheering, Inner Sakura was able to force Ino from her body before she could do so. With both girls exhausted from the amount of effort they'd been putting into their fight, Ino and Sakura charged at each other to deal final blows. Striking each other simultaneously, both were knocked out, leading to a draw. As the two recovered, Ino and Sakura began to rekindle their friendship. Though when Ino declared that she wasn't going to just hand Sasuke over to her, Sakura became angered and declared that the same went for Ino as well.

Invasion of Konoha Arc
A month later, while watching Naruto and Sasuke's matches during the finals and marvelling at how their abilities had improved, the invasion of Konoha began. Sakura was able to repel the sleep inducing genjutsu that spread throughout the stadium. Because of this, and because Sasuke had pursued Gaara, Kakashi tasked Sakura with waking and assembling a team to go after him. Upon catching up with Sasuke, Sakura protected him from Gaara's attacks, risking her life to put herself between him and danger. Gaara used his sand to immobilise her, and as the sand slowly suffocated Sakura, Naruto fought to defeat Gaara using Sakura as inspiration to not give up, and save her. After Naruto defeated Gaara, Sakura was freed. Later, Sakura thanked Sasuke for saving her, but he explained to her that it was Naruto who had saved her, and she turned to smile at Naruto, not noticing the scowl on Sasuke's face as she did so. She later attended the Third Hokage's funeral.

Search for Tsunade Arc
Sakura approached Sasuke thinking that he saved her but Sasuke reveals that it was Naruto much to Sasuke's dismay and Sakura looked surprised.

Sasuke Retrieval Arc
As time goes by and Sasuke's lust for power grows stronger, Sakura grows concerned that he may abandon Konoha to seek out Orochimaru. Although she spends as much time with him as she can in an effort to deter him from this path, Sasuke finally defects. Having suspected this would happen, Sakura met him at the village's exit, doing what she could to stop him. When it seemed that he was still going to leave, Sakura declared that she was in love with him. She said she would do anything for him, even offering to help him in his quest for power, so long as she could be with him. Sasuke then turned to her and called her annoying. Sakura then threatened to scream and alert the village of his betrayal. Sasuke gives her a soft "thank you" before knocking her unconscious and leaving the village. When she awakens the following morning she tells Kotetsu Hagane and Izumo Kamizuki, who in turn reports to Tsunade about his departure, leading to the formation of the Sasuke Retrieval Team.

When Naruto set out the next day to retrieve Sasuke, Sakura came out to meet him. Sakura begged for Naruto to bring Sasuke back, believing Naruto to be the only person who could get through to Sasuke. Naruto, looking at the crying Sakura, promised her that he would bring Sasuke back, making it his promise to her for a lifetime. This brought more tears as Sakura realised that Naruto knew how she felt and that he had always been there for her.

After Naruto failed to bring Sasuke back and was left hospitalised in the process, he apologised to Sakura for his failure and asserted that he would definitely keep his promise. Inspired by Naruto's determination, she replied that, next time, they would retrieve Sasuke together, and that she would be there to help him from now on. Determined to never be useless again and to save Sasuke and help Naruto, Sakura then asked to become Tsunade's apprentice, a request which Tsunade happily accepted.

Pre-Shippūden Filler Arcs
The only filler arc Sakura plays a major part in is the Land of Rice Fields Arc, where she, Naruto and Jiraiya tried to save Sasuke. In the end of the arc Sakura asks Tsunade for medical training.

Hence, little was seen of Sakura during the filler arcs, much of her time being preoccupied with training. She did appear when she, Chōji, and Naruto has to help rescue Ayame, the daughter of Teuchi. To save the daughter, Sakura and her team-mates were forced to create the perfect ramen, to which Sakura assisted by pounding it to its shape.

When she did go out on missions with her fellow genin, Sakura served as the medical specialist, healing the wounds of others and examining bodies. Ino, jealous of Sakura's new-found healing abilities, asked to train with Sakura to be a medical ninja. To Ino's dismay, Sakura immediately proclaimed that Ino would be her junior during the course of the training.

Kazekage Rescue Arc
After Naruto returned from his two and a half years of training abroad, Sakura was one of the first villagers to greet him, and was happy to see him, even noticing he was now taller than she is. However, this doesn't last long, as Sakura asked him if she had changed, to which he responds she hadn't and that she was the same old Sakura. The results of her training with Tsunade first show themselves when she punches Naruto for attempting to demonstrate a new perverted technique for Konohamaru. Kakashi soon recruited both of them into Team Kakashi and issued another bell test, this time the goal actually being to take the bells. Both are able to show off their new abilities. She shocks Kakashi and Naruto when she uses her super strength taught to her by Tsunade, but in the end are only able to take the bells by tricking Kakashi.

After returning from the bell test, they learned that Akatsuki had captured Gaara. Team Kakashi was assigned to go to Sunagakure to help rescue him. Upon arriving in Sunagakure, Sakura used her new medical expertise to save Kankurō from a poison given to him by the Akatsuki member Sasori. Sakura then made a few antidotes to counteract the poison in case anyone on the team should have need of it. The antidote in hand, Team Kakashi followed Akatsuki's trail, accompanied by Chiyo, a Sunagakure adviser. During this period of time, Sakura first learned that the Nine-Tails is sealed into Naruto.

Once they arrived at the Akatsuki lair, the team split up, Chiyo and Sakura fighting Sasori while Kakashi and Naruto went after Deidara and Gaara's body. With both Sasori and Chiyo being master puppeteers, and with all of Sasori's attacks being imbued with his poison, Chiyo controlled Sakura like a puppet to improve her dexterity allowing her to get close enough to Sasori to destroy his puppet armour Hiruko.

As Sasori summons his the Third Kazekage puppet, much to Chiyo's shock, he begins employing the former Kazekage's ability which he had combined with his own poison. As the battle ensues, with Chiyo's help, she eventually deduces the puppets movements, Sasori's attack pattern and is ultimately able to destroy it. Revealing that he had turned himself into a puppet as well, Sasori gained the upper hand in the fight and later summoned one hundred puppets to fight against Chiyo's White Secret Technique: The Chikamatsu Collection of Ten Puppets. After being sealed by Chiyo, Sasori moved to another puppet body and tried to kill her, only for Sakura to step in as a human shield. With him being distracted, Chiyo stabbed Sasori through the heart. As his life waned, he relished the fact that Sakura would die too, only to be proven wrong by the combination of Sakura's antidote and Chiyo's healing abilities. As a reward for defeating him, Sasori spent his last breath to tell Sakura of a spy within Orochimaru's ranks.

When they caught up with Naruto and Kakashi, Sakura tried to revive Gaara, only to discover that he was already dead. As Chiyo surrendered the rest of her energy to resurrect Gaara, she told Sakura not to give her life for an old woman and predicted that someday she would surpass her master as a kunoichi. After attending Chiyo's funeral, the team returned home.

Sasuke and Sai Arc
With the information gained from Sasori, Team Kakashi decided to use this as an opportunity to find Sasuke. Because Kakashi was still bedridden after his encounter with Deidara, Yamato led the team instead. Sai was also added to the team as Sasuke's replacement, but neither Naruto nor Sakura were willing to view him as such, and had difficulties getting along with him. In fact Sakura even punched him for insulting Sasuke. Their mission being to meet with and capture the spy, Yamato, disguised as Sasori, went on ahead. When the spy, Kabuto Yakushi, ended up being in league with Orochimaru, Yamato called in the team for back up.

Naruto quickly engaged Orochimaru in combat, and Sakura was surprised by the very danger of his tailed forms. She was then knocked out after Kabuto was thrown away by Naruto and slammed into her. After regaining consciousness, she realised that Naruto had advanced to his four-tailed form. She recalls on who Naruto used to be, his happy personality, and his promise to her, then feeling guilt for the monster he had become and his suffering, she starts to cry and call for him to stop. When Sakura approached him to try and bring him to his senses, he attacked and injured her, unaware of what he was doing. Kabuto attempted to heal her wound, saying that they were both enemies of Akatsuki. All he could do was close it, however. Once Yamato forced the Nine-Tails' influence to recede, Sakura tended to his wounds. While healing Naruto's wounds, she tears more on how she wishes she could be of more use to Naruto rather than just healing him after a battle. Yamato tells her that she does much for Naruto by just caring for him just before Naruto awakens. He recuperated, and they continued on to Orochimaru's hideout, where Sakura crashes to the ground due to her injury from Naruto, and she refuses to tell him the cause. where Sai finally proved his worth by helping them find Sasuke. When they were unable to persuade Sasuke to come home with them they attacked him instead. Sakura was able to determine how his Chidori Current worked, and charged him after charging her fist, attacking Sasuke for the first time ever. However, when Sasuke attacked her with a massive amount of killing intent, Yamato intervened and took the attack for Sakura. In the end, Sasuke fled with Orochimaru and Kabuto, and Sakura told Naruto very determinedly that tears weren't going to bring Sasuke back. Then, they returned to Konoha.

Hidan and Kakuzu Arc
Team Yamato was sent to provide back up for Team 10 during their battle with Akatsuki. Because Shikamaru was separated from the rest of the group, Sai and Sakura were sent to assist him, though upon arrival they found that Shikamaru had already defeated his opponent. Having not taken part in the battle, Sakura returned to Konoha with the others, and later healed the damage to Naruto's arm from the use of his new technique. Because this made it difficult for him to eat, she offered to feed him. Though he was delighted by the idea, interference from both Sai and Kakashi prevented this from happening. Shortly afterwards they left to find Konohamaru, who had just revealed to have mastered the Shadow Clone Technique. He showed them his variations on the Sexy Technique, one of which excited Sakura.

Itachi Pursuit Arc
When news reached Konoha that Sasuke had killed Orochimaru, Sakura and Naruto were the first to join Kakashi's Eight Man Squad, and began the hunt. During her search, she barely missed a member of Sasuke's Hebi, Karin, and later regrouped with the others. When Kiba caught Sasuke's scent, the group followed until they encountered Tobi. Sakura initially suspected that he was using genjutsu or clone techniques, but after Hinata pointed out that his chakra remained in one location and Tobi managed to escape Shino's bugs, she realised that he was removing parts of his body from existence. She attempted to head to Sasuke's location with her team, but Tobi had already taken him away.

Invasion of Pain Arc
Once they returned to Konoha and learned of Jiraiya's death, Sakura tried to comfort both Naruto and Tsunade. When Naruto blamed Tsunade for the death of Jiraiya, Sakura scolded him. She was then shocked to hear Naruto declare that he would get his revenge. She later tried to help decipher Jiraiya's dying message to find out more about the Akatsuki leader, Pain, but was interrupted by Pain's attack on the village. After saving some villagers and killing Pain's Giant Centipede, Sakura went to the Konoha hospital, where she was quickly asked to lead the medical front defending the building and healing what injuries she could, impressing Chōji through her leadership and skills.

When Pain destroyed the village, Sakura was saved by Katsuyu. When she sees the village in ruins she cries out for Naruto to return to save everyone. After Naruto's return Sakura could only watch as Naruto tried to defeat the six Pains. She became worried when Naruto entered his six-tailed form, and was amazed to find out that Hinata risked her life to try and save Naruto because she loves him. She heals Hinata afterwards and watches as Pain, defeated and converted by Naruto, revives all those who had died during his attack. When Naruto came back to the village after talking to Nagato, Sakura punches Naruto calling him rash for taking on Pain by himself but then hugs and thanks him for saving them.

Five Kage Summit Arc
Sakura is later seen in a tent along with Naruto, Kakashi, and Shizune, telling them about Tsunade going into a coma, and that neither she nor Shizune could do anything for her. She tried to cheer Naruto up, but her effort was interrupted by the arrival of Kiba. Kiba told them that Danzō Shimura has replaced Tsunade as Hokage and that he has ordered Sasuke to be executed as a missing-nin. Naruto and Sakura, hoping they might be able to convince Danzō to change his mind, asked Sai about him. Sai is unable to tell them anything, but their questioning attracted the attention of Omoi and Karui. The Kumogakure ninja informed them of Sasuke's crimes and demanded any information they may have on Sasuke. Seeing how upset this made Sakura, Naruto volunteered to tell them for her the information they wanted to know about Sasuke.

Naruto, along with Kakashi and Yamato, went to the Land of Iron to ask the Fourth Raikage to forgive Sasuke. While they are gone, Sai informed Sakura of the lengths Naruto has gone to make her happy. He also said that although Naruto loved her, the strain of trying to bring Sasuke home and fulfilling the promise he made to her, cause him nothing but constant pain. Shikamaru joined the conversation on behalf of the other members of the Konoha 11, telling Sakura that Sasuke's actions will only lead to war. Believing that the best course of action would be for them to personally stop Sasuke, Shikamaru asked for Team 7's consent. Sakura agreed, but insisted that she be the one to tell Naruto.

Sakura, Sai, Kiba, and Lee went to the Land of Iron to talk to Naruto. After they located him, Sakura made a false confession of love to Naruto and claimed she no longer cares about Sasuke and encouraged him to give up on the promise he made to her. Naruto, knowing very well that she's still in love with Sasuke and that she doesn't love him, does not believe her and says she is lying to herself. Angered by this, she insisted it was true and then pushed for Naruto to forget his promise to her and focus on the fact that Akatsuki is after him. Naruto, in turn, said that he was also pursuing Sasuke for his own reasons, not just because of his promise to her. Again, furious by this, Sakura left with her group. Ignoring Kiba's questions about why she hasn't told Naruto their plans, she asked him to help her find Sasuke. When they start nearing Sasuke, Sakura tried to set off a knockout gas to incapacitate Kiba, Sai, and Lee. Sai stopped her and, having told Naruto and Kakashi about their plans, instructed them to wait for Kakashi to arrive. She convinced Kiba and Lee to fight Sai with her, but used the knockout gas on them as they began to scuffle.

Sakura found Sasuke about to kill Karin. She stopped him and told him that she wanted to join him, even if that means betraying Konoha. Suspicious, Sasuke told her to show her resolve by killing Karin. Pretending to agree, Sakura approached them, thinking that if she killed him now, it will all be over. Karin interrupted her by warning her that Sasuke was about to kill her, but his attack was blocked by Kakashi. Kakashi instructed Sakura to heal Karin and to leave once she had done so. However she snuck up on Sasuke and tried once again to kill him, but she then started to remember all the times they had together and she was ultimately unable to bring herself to do it.

Sasuke noticed Sakura and seized her by the throat and attempted to kill her, she was then rescued by Naruto. Naruto then prepared himself to attack Sasuke after Kakashi tells him and Sakura that he will personally take care of Sasuke and wishes for them not to witness it. Kakashi states that Sakura's kunai was crafted by Sakura herself, with poison learned from Shizune, and that it would most likely not work as Orochimaru would have made him immune to it. After Naruto voiced his determination that he and Sasuke will die together one day in battle, and that he would shoulder Sasuke's hatred as a friend, Sakura was touched by Naruto's determination, and showed her gladness that he showed her a way for Team 7 to still have a happy ending. However, Naruto suddenly collapsed from the poison kunai that Sasuke used to nick Naruto's face when he saved Sakura from him, and Sakura panicked, and gave him an antidote on Kakashi's request. After Sakura gave Naruto the antidote, Naruto says he still feels sick. When Naruto asks who Karin is, Sakura replies that she's a partner of Sasuke, which Karin denies. When the group are ready to leave the bridge, Kakashi reminds Sakura that she left something behind to which he is refering to Kiba and the others. Team 7 and Karin are later seen with the sleeping Kiba, Akamaru, Lee and Sai and Kakashi expects Sakura to apologise to them after they awake to which she will.

After returning to Konoha, Sakura is seen present with the rest of her friends, wondering as to what Naruto is hiding from them, remembering his statement about his and Sasuke's death in a possible fight. She is then seen out of breath when she meets up with Naruto at the Ramen Ichiraku, and she is happy to inform him that Tsunade is awake. Teuchi then offers her a bowl but, being in a rush to tell people the good news, she turns it down. She then tells Naruto she will see him later.

Confining the Jinchūriki Arc
In the anime, Tsunade tells Sakura that they will go to war with the Akatsuki and Sasuke.

Shinobi World War Arc
Sakura is placed within the Third Division and is later seen using her Mystical Palm Technique to heal Might Guy and wondering how he got to be in this condition right before the war, while a worried Lee looks on. Later on, Sakura is seen with her division as a red flare goes off and Kakashi orders them to go the Surprise Attack Division. Along with her division, they encountered Zabuza and Haku who were about to attack the Surprise Attack Division. She was shocked to see Zabuza and Haku again.

After Haku and Zabuza's personalities were wiped out along with those of Pakura and Gari, Kakashi orders his squadrons to group themselves around the sensor ninja in the Manji Formation. Lee then tells Sakura that he'll protect her no matter what, to which Sakura tells him to also be careful as last time Zabuza attacked from the only weak spot of the formation: the centre. When the battle began in earnest, Sakura began healing the wounded.

As the battle came to a halt when night fell, Sakura went to the Logistical Support and Medical Division compound to heal all the wounded that were being moved to a central location. She attends to an unknown ninja's wound before Neji arrives. After she finishes she tells him that he should take the opportunity to get as much rest as possible. She is later seen outside one of the barracks after being alerted that three jōnin level medics were killed by an unknown assailant. When they surmise that a spy must've entered their numbers despite their stringent security measures, she dismisses the Transformation Technique as their method as the sensors would've detected them and assumes that one of their own must be under the enemy's control. Later as she prepares to start her rounds again, she is approached by the ninja she had healed earlier who hands her a love letter saying that he didn't know if he'll survive the war or not. She takes the letter and thanks him, but tells him that she loved someone else.

After one last compliment, the Iwa shinobi leaves the tent visibly disappointed that Sakura was in love with someone else, Sakura soon afterwards becomes saddened as she starts thinking about Sasuke. Moments later, Neji then enters her tent asking her if she was ok. He then tells her that he doesn't blame her for being upset given the current situation. Sakura says that they need to be vigilant to which Neji agrees. He then asks for Shizune as he had made some headway in uncovering who the culprit was. Sakura tells him that she's attending to Tonton who had sprained her leg. Neji then says it's better than her arm to which Sakura agrees that she would still be able to form seals. He then asks her to take a look at his hand again to which she agrees, telling him to sit down. As he draws for a kunai to kill Sakura, she slams him to the ground. Surprised he inquires how she knew and retorts that piglets don't have hands. After being punched the transformation technique wears off and the White Zetsu clone resumes his original appearance. Sakura then interrogates the Zetsu about how he was able to get onto the compound undetected. Together with this information and a report Yamato had compiled on Zetsu, she pieces together the Zetsu's abilities and then leaves the clone in the hands of two shinobi to inform headquarters of this latest discovery.

After reporting the findings to Shizune, they then perform an autopsy on the body of the clone and realises the similarity in their DNA to that of Yamato and by extension, Hashirama's. They then begin to piece together the truth behind the White Zetsu Army clones.

The next day, in the anime, at the Logistical Support and Medical Division, Hayate Gekkō, a Sunagakure shinobi, and a Kumogakure shinobi attacked the Medical camp to retrieve the KIA scroll and left. Sakura, Yūgao Uzuki, and a few shinobi has gone after them to retrieve the scroll. As they managed to catch up to them, they fought them off and managed to seal the Kumogakure and Sunagakure shinobi away but couldn't managed to seal Hayate because of the injured and he escaped. Sakura has healed the injured and ran off to have a talk with Yūgao and listen to her past life of Hayate. Sakura ran off to pursue Hayate on her own and was told she became a fine shinobi. As she fought off Hayate, Yūgao came to her aid and defeated Hayate and he is sealed away.

Later, as more wounded were brought to Sakura, she was surprised to see that one of them was the boy Yota from years ago. Happy to see Sakura, he began making snow appear and dancing around. Soon afterwards, the snow's intensity began to increase, overwhelming Sakura.

Later, Sakura was approached by a pair of ninja, one of whom appears to be gravely injured and the other desperately requesting her assistance. The Akimichi guarding the medics is adamant that they stay back, uncertain of who's who. Sakura, unable to turn them away after hearing the kunoichi beg them not to let her husband die in her arms, agrees to help. The pair then reveal themselves as imposters and attack. Before she can be attacked however, Naruto's shadow clone promptly takes them down, much to the surprise of Sakura and Shizune. After being informed by Inoichi from HQ that Naruto and B were fighting the "masked Madara", Sakura and the rest of the Konoha 11 rush to his aid. As she runs, she thinks to herself that Naruto always got left with insurmountable tasks but this time would be different as not only her, but everyone would be there fighting alongside each other this time.

Ten-Tails Revival Arc
Upon arriving at the battlefield, she immediately began to tend to the wounded Kakashi and Might Guy. She later stood with the remaining members of the Allied Shinobi Forces as they prepared to face their opposition. Positioning herself behind Darui to lend support when necessary, Sakura was buffeted by the Ten-Tails as it emerged from the hole it had been trapped in. Narrowly dodging the wooden stakes being fired by the Ten-Tails, Sakura later watched on in horror as Neji sacrificed his life to protect both Hinata and Naruto. Sakura was later seen on the battlefield with Naruto and the others and has received chakra from Naruto, Sakura was then attacked by Obito ejecting multiple weapons at her and two others they where protected by Kurama's chakra tail.

After having survived the Tenpenchii attack, Sakura and the others rallied around a wounded and exhausted Naruto where behind a defensive line, Sakura healed his injuries. As the Ten-Tails grew impatient with the situation, it proceeded to open its maw and prepared to fire an even larger Tailed Beast Ball. With the shinobi losing hope, Sakura rallied the troops with a rousing speech in which she declared that she would do her all to heal Naruto completely, and that no matter what they should not give up fighting, because if they were to die any way, it would be better not to simply give up. When the Ten-Tails created an enormous Tailed Beast Ball which it fired at the Alliance, she watched on as Shikamaru initiated his strategy, having the Alliance create multiple defences and a transformed Killer B tried to deflect the attack to no avail. When the Tailed Beast Ball disappeared, Sakura looked on in shock as the Fourth Hokage appeared before them, asking his son, if he were late.

Questioning who the person before them was, Sakura is later shocked as the ocean behind them rose up, and the stranger before her simply noting that he had sent the Tailed Beast Ball out to sea. Akamaru's behaviour soon alerted Sakura and the others to the fact that Mianto had been reincarnated, but the Fourth waves down their suspicions noting that he was on their side. When he questions his son about Sakura being his girlfriend, Naruto's response prompted Sakura to headbutt him for lying to him for being intimate, the action reminding the Fourth of Kushina. Sakura, though puzzled by Minato's words that Naruto's friend was also on his way, looked on as the other previous Hokage arrive on the battlefield, and Minato donned a chakra mantle similar to that of Naruto's. After the Ten-Tails was immobilised, Sakura stared in disbelief as Sasuke appeared before them. Questioning his reasons for coming to the battlefield, Sakura and the other members of the Konoha 11 are shocked to hear Sasuke announce that he would become Hokage. As Sasuke and Naruto leave to enter the battle, Sakura disregarded Naruto's advice to rest while they took care of it. Telling them that she was not a weak woman and had also been trained by a Sannin, Sakura noted that she had almost stored up enough chakra to unleash her true power and she would not stand by and watch them. With this, the trio look on as Naruto happily noted that the original Team 7 had been reborn.

Naruto the Movie: Ninja Clash in the Land of Snow
Sakura joined her fellow members of Team 7 on a mission to protect the actress Yukie Fujikaze, as she and the production group she worked for travelled to the Land of Snow. Throughout the movie, Sakura encountered the Yukigakure-ninja Mizore Fuyukuma, and eventually distracted him with her Sakura Blizzard Technique. She was later seen looking out at the newly created Spring country, holding Sasuke's head in her lap.

Naruto the Movie 2: Legend of the Stone of Gelel
Sakura was sent out on a team with Naruto and Shikamaru to deliver a pet ferret to a village where its rightful owners could pick it up. After arriving and finding the village in ruins, they were attacked by mysterious warriors led by Temujin, a knight wielding the power of the Stone of Gelel. Their conflict with him resulted in Sakura and Shikamaru becoming separated from Naruto, only to rejoin him later after several conflicts with Temujin's allies. During a final battle with the wolf-like Fugai, Sakura killed her by using metal pillars to reflect her ear-splitting howl, which caused the pillars to collapse in on her.

Naruto the Movie 3: Guardians of the Crescent Moon Kingdom
Sakura was assigned along with Naruto and Rock Lee to protect the Land of the Moon's prince during his world trip. Sakura displayed some of the immense strength learned from Tsunade by destroying a wall with a single punch, and her improved taijutsu skills during a fight with genjutsu user Karenbana, who was hired to kill the prince. For Sakura's second fight with Karenbana, she could tell where she was because she could smell her perfume. Sakura was almost knocked out during her first encounter with Karenbana. During her second encounter with Karenbana, Sakura got trapped in Karenbana's genjutsu, resulting in her being knocked out by Karenbana, then after waking up (before the final blow), she shattered a chandelier above the two combatants' heads with two thrown shuriken, causing glass to fall on the floor. Sakura was then able to hear Karenbana's movements by the sound of the glass crunching under her feet. Sakura delivered a bone-crushing punch to Karenbana's jaw, ending the genjutsu and the fight. In the movie, Sakura used some healing techniques on the King and tried to heal an injury.

Naruto: Shippūden the Movie
Sakura was assigned to protect and escort Shion, the head priestess of the Land of Demons, to the tomb of the ancient demon Mōryō. To aid her in this mission, she was joined by Naruto, Lee, and Neji (who was assigned as team captain). Upon their arrival at the temple, Sakura and her team were forced to face off against a group of ninja, with unusually powerful mastery of elemental ninjutsu. Sakura used her tremendous strength to aid Lee in fighting them off as Neji went in search for the priestess.

During the journey to Mōryō's tomb, Sakura was put in charge of carrying Shion, something the latter claimed was very uncomfortable (causing Sakura to go into a fit of rage), but she was paralysed after Kusuna injected her with his Secret Anaesthesia, causing her to fall off a tree, but luckily Neji caught her and had enough time to recover. After a hard battle with Shizuku, Sakura was able to join her team in taking down their opponents by first tricking them into using up their medically-enhanced chakra.

Naruto Shippūden 2: Bonds
Sakura was first seen at a hospital during/after the attack on Konoha, and commenting on the injured villagers who had been saved by the mysterious old man, Shinnō. Sakura was assigned with Naruto and Hinata to escort a boy (who was really a girl) named Amaru, and Shinnō, her sensei, back to their village. During their journey, Sakura and Naruto were separated from Hinata. They both then found the Zero-Tails, which fed on the darkness of human souls and somehow took over Amaru's body. Sakura tried to fight it, but was defeated easily. She was then left behind when the ruins began to fly away, and only reappeared to watch the ruins explode from Naruto's repeated Rasengan attacks. Sakura was last seen lecturing Naruto at the end, most likely for being so reckless. Hinata was talking to her afterwards, probably telling her about Sasuke.

Naruto Shippūden 3: Inheritors of the Will of Fire
Sakura was first seen with Naruto and Kakashi when Sai got ambushed by a bunch of birds which knocked him down and Naruto aided him and both got attacked, only to get saved by Kakashi and Sakura. Sakura healed both of them and forced them into the hospital bed. Naruto and Sai who both got out of the hospital bed and went to the restaurant to celebrate their recovery both got slapped by Sakura for leaving the hospital. After when Hiruko announced a Fourth Ninja War will start, Sakura was one of the Konoha 11 who got assigned to secure the village. Later Tsunade said that Kakashi is a missing-nin and that they shouldn't go after him. She got dismissed and overheard Tsunade's talk with Shikamaru that Naruto is locked up. She went there to go see him and he told her how Kakashi was controlled and he's planning to die for the village. Sakura broke the cell and freed him then they both went after him.

On their way they found Kakashi, but got stopped by Shikamaru and the rest of the rookies. Sakura and Naruto both stated that they're going to rescue him no matter what and that they won't abandon their sensei. They got ambushed; Shikamaru decided they can go ahead while they hold off the enemies. Sai later comes and brought Naruto and Sakura with him on the ride to save Kakashi. Gaara then attacked them and said that he won't let them go any further. Naruto then fought Gaara while they went ahead. When they found Kakashi, he was still under the technique that Tsunade put on him, and Naruto, Sakura, Sai, and Shikamaru all engaged Hiruko in battle, but due to lack of knowledge of the bloodlines he acquired, they were defeated. After Naruto saved Kakashi, Sakura engaged the combined summon form of Hiruko's minions with the rest of the Konoha 11 while her team-mate and sensei fought Hiruko himself. After the battle, Sakura stood victorious with her friends while smiling softly.

Naruto Shippūden 4: The Lost Tower
Along with Naruto, Sai and Yamato, Sakura is assigned to capture Mukade, a Konoha missing-nin whose purpose is to get the power of the Ryūmyaku from the ruins of Rōran, once a glorious city which was destroyed during the war. Mukade manages to absorb the seal the Fourth Hokage used and is engulfed by a huge light. Naruto tries to stop him and disappears along with Yamato. Sakura tries to follow them, only to be stopped by Sai's ink bird while she cries and screams Naruto's name.

Almost immediately after, Naruto and Yamato come back from the past but they don't remember what happened to them. As Team Kakashi leaves the ruins, they are approached by a girl who claims that she felt a disturbance on the Ryūmyaku. The girl says she's the daughter of the former Queen of Rōran and bears a Konoha Chakra Blade, telling them that her mother received it from a hero in a dream. As she leaves, Naruto claims that he has the feeling he saw her in a good dream. Annoyed, Sakura then grabs and pulls on Naruto's ear and yells at him for being a pervert.

Naruto 5: Blood Prison
When Naruto was summoned to Tsunade's office and accused of attacking the A|Raikage, Sakura was the only one who tried to defend him and believed that he was innocent, even though he was still taken away in the end. During Naruto's time in Hōzukijō, he reflects on his bonds with his friends and comrades in Konoha, where a flashback of Sakura punching Naruto's face is shown. In the end of the movie, Sakura is again shown with Shizune and Tsunade, and returns Naruto's headband. When Mui dies and the Fire Release: Heavenly Prison is released, Sakura and the rest of the Konoha 11 stop the prisoners from escaping. She tries to heal a dying and impaled Naruto after his battle but cannot. Ryūzetsu arrives and is able to save Naruto with her Dragon Life Reincarnation. Naruto awakens to see Sakura trying to heal Ryūzetsu, to no success. They later all prepare to go home. It is shown after that immediately when Naruto was taken out of Tsunade's office, Sakura and sigh in relief and reveal to have been faking the "surprise" of Naruto's accusation, Sakura even asking if she was "convincing enough".

Naruto 6: Road to Ninja
Attacked by Tobi, Sakura ended up being sent alongside Naruto to another world by the mysterious new dōjutsu. Other than finding her friends, along with Sasuke, being the exact opposite of who they normally are and being terrified of the alternate Hinata's boldness towards her, Sakura learns that her parents died in this world and her father was the Fourth Hokage. She enjoys the fact that the alternate Sasuke flirts with her and actually returns her feelings by giving her a rose that makes her shy with him. She later sees him giving roses to a lot of other girls, breaking her heart. She is also saddened that he's not the Sasuke that she fell for. The world they are sent to is the result of Sakura's wish of being free of her parents as she wanted to be free of parental control from them, while Naruto wants a world where he has his parents, however, as she has some time without them, at first she enjoys it, she realises she made a mistake and begins to understand Naruto's pain of not having parents and realising how lonely Naruto has felt growing up and how she took him for granted about not having parents and feels guilty for wishing she didn't have parents, as she took them far too lightly.

As the events occur, the Sakura of the other world ends up in Konoha with similar confusion as Ino and the Konoha 11, believing her to be their Sakura with memory trouble, try to help her by acting out their other-world counterparts. But upon seeing the Kizashi and Mebuki of that world while looking for her necklace, the other Sakura tearful regains her memories and thanks Ino for her help before teleporting away, leaving the girl confused.

Video Games
In video games set during Part I, Inner Sakura is used as a technique due to Sakura's lack of technique of her own. Sakura has also shown a talent for genjutsu in some video game appearances, most involving Inner Sakura.

Creation and Conception
Although Sakura is the most recurring female character in Naruto, Masashi Kishimoto did not originally intend for Sakura to be the heroine of the series, even stating on occasion that he still has a hard time viewing her as a heroine. Kishimoto attributes this to him being unable to draw good heroine characters, and fashioned Sakura as a girl who cannot understand men, the best example of a heroine he could come up with. Sakura's creation is a result of Kishimoto's desire to make a somewhat irritating character who was well-intentioned. Despite these elements, Kishimoto grew fond of Sakura, feeling that many of her personality traits are common among all people, thus giving her a sense of real humanity.

When designing Sakura, Kishimoto focused on her silhouette and created a costume as simple as possible. This is a divergence from the other main characters of the series, whose costumes are very detailed. The leggings are the most notable aspect of her design, as they are meant to show that she is very active. At the start of the series her leggings extended below her knees and closely resembled trousers. As Part I progressed, the leggings became increasingly shorter and tighter. Similar to his inexperience with drawing heroines, Kishimoto lacked the experience needed to make Sakura "cute" when he first began drawing her. Although he implies that her appearance has become cuter since then, Kishimoto and much of the Naruto manga staff agree that Sakura was "far from cute" at the start of the series.

Sakura's most well-known physical characteristic is her broad forehead. Because of this, Kishimoto at times focuses too much effort on drawing it in scenes or promotional artwork where Sakura is featured prominently. This results in her forehead appearing too large. When designing Sakura in her Part II appearance, Kishimoto decided to change her clothes to a more lively karate suit style. The upper part, though, still has a China-esque feeling to it, so as to make her more feminine.

In colour illustrations of Sakura from Part I of the manga, her leggings, boots, and forehead protector are almost exclusively depicted as being teal, and she frequently has her nails painted sea-foam green, with matching or pink eye shadow. In the original Naruto anime, however, her leggings are a darker green and her forehead protector and boots are the same blue as those worn by other ninja, and she wears no visible cosmetics. Her colour scheme in Naruto: Shippūden accurately reflects her appearance in colour illustration from Part II of the manga.

Kishimoto's staff have said that Sakura's pink hair was originally intended to give her a unique style and to resemble cherry blossoms, after which she is named.

Trivia

 * The name "Haruno" means "spring field", and the name "Sakura" means "cherry blossom", a flower which is cherished in Japan due to its beauty and its almost-tragically short life span (cherry blossoms have historically been associated with the samurai). The cherry blossom also serves as the national flower for the nation of Japan. In Japanese, means "spring field of cherry blossoms", which may be an origin of the name. It can be also used in the game, Hanafuda, as a month card of.
 * Sakura's name, when read as, can also be interpreted as "cherry blossoms in spring".
 * In the June 2006 issue of Shōnen Jump, Kishimoto stated that Sakura would be the best ninja instructor out of Team 7 and is the closest to being normal, despite having flaws in her personality.
 * In the Naruto character popularity polls, Sakura was placed 5th in the first, 14th in the second, 9th in the third, 10th in the fourth, 8th in the fifth, and 12th in the sixth. She finished 6th in the seventh with 9,701 votes and in the newest poll, she tied with Sai in 12th place.
 * Sakura had one of the longest battle scenes in the anime (eight full episodes), giving her roughly three hours of battle screen time. This is when she and Chiyo were fighting Sasori.
 * In the seventh Naruto Shippūden opening, Sakura was shown fighting Konan with Ino and Hinata, though in the manga, they did not fight her.
 * Despite being the heroine of the series, Kishimoto stated himself during the 2010 interview that Hinata would make a better heroine than Sakura, this is due to the fact that because Sakura not only has a 'normal' background in comparison to Hinata but also because he has a hard time making good roles for female characters like Sakura, having stated on several occasions that he has a very hard time viewing her as the heroine of the series. However, Kishimoto also stated that he would try to have Sakura play more of a heroine role in the future.
 * Her hair is shown quite different between the anime and the manga. Her hair was not too long in the manga for her first appearance. The hair also seems much longer in the anime after the haircut in Chūnin Exams. Sakura also shown with a shoulder-length spiky hair in Part II of the manga and in Part II of the anime her hair is straight and a little shorter.
 * According to the databook(s):
 * Sakura's hobbies are playing trivia games and memorising new material for her medical studies.
 * Sakura wishes for a rematch with Ino.
 * Sakura's favourite foods are syrup-coated anko dumplings, umeboshi, and anmitsu, while her least favourites are anything spicy.
 * Sakura has completed 34 official missions in total: 12 D-rank, 9 C-rank, 6 B-rank, 7 A-rank, 0 S-rank.
 * Sakura's favourite phrase according to the first databook is and her favourite word according to the second and third databooks is.

Quotes

 * (To herself about Naruto) "Always acting like a fool who only knows one thing… Hokage, Hokage. I'm sorry Naruto… that impossible dream of yours… I don't want to see it crushed!"
 * (To herself) "I've always considered myself to be a true ninja… but those were just empty words, because Sasuke and Naruto were always in the lead! But now it's my turn to take the lead, and all of you can watch me from the background!"
 * (To herself, about Ino) "Ino… I have always believed those words you told me. I always hoped they were true. I wanted to be like you. You were my goal. Thanks to that, I'm here now. That is why, Ino, I want this to be an all out fight. Unless I… really surpass you, it's meaningless."
 * (To Ino) "Didn't you know? Women have to be strong in order to survive!"
 * (About Naruto) "I… kinda envy your strength, Naruto…"
 * (To Sasuke) "I… I love you with all my heart!… If you were to stay here with me, there would be no regrets… because every day we'd do something fun, we'd be happy I swear!… I would do anything for you! so… Please just stay with me!"
 * (To Chiyo) "I may not have amazing weapons like a puppet in me, but what I do have is my master's contempt for losing!"
 * (To Yamato) "Same as always… I can only do the dumbest of things for Naruto…"
 * (About Naruto) "I'm the one who made Naruto suffer the most… I've just been getting it wrong… just been messing it up… I don't want to get it wrong anymore… don't want to screw it up anymore."
 * (About Naruto and Sasuke) "Naruto's here because he's made up his mind… my resolve is nothing compared to his now! I'm supposed to be a ninja, but all I've ever done is lean on him and cry… I was supposed to change that… I came here and I thought I was ready. But I can't do anything… I can't say anything. The only thing that remains for me… is to believe in them!"
 * (To herself) "Naruto… You saved Konoha… And now you're trying to save the entire shinobi world… You always get left with these insurmountable tasks… But no matter what you say this time, we're going to be together… Not just me… We're all going to fight together this time!"
 * (To the Alliance) "I'm going to make sure Naruto has a full recovery! Every one of us must do what's in their power! If we're going to die any way… …then its better to die fighting than to do nothing!!"