Board Thread:Versus Debates/@comment-26636534-20160221130323/@comment-734582-20160416135849

BakumatsuWarrior wrote: Had the Yata Mirror not been there, Guy could simply use Hirudora to thrash Itachi and his Susanoo. The strain from Hirudora, combined with the incredibly painful strain produced by the Susanoo, would quickly exhaust Itachi.

Considering that Susanoo can not block sound, there's a good chance that Hirudora, being a pure displacement of air, will plain defeat Itachi. And since Yata was not used to block that sound ability, well i think it's safe to say it can't do that.

Normally i'd say itachi wins, but Guy's experience with fighting Sharingan users and Genjutsu (he was Kakashi's rival after all) is enough to swing this in his favor.