Board Thread:Naruto Discussions/@comment-24312338-20180222140450/@comment-34752936-20180320074758

JamesDuh wrote: Rachin. I don't deny the boost it gives is incredible. But surely you can agree the boost she gets for storing chakra for a year will be far greater than the boost she gets for storing chakra for a week. That's why I'm saying it isn't necessarily a 100x multiplier. It just depends on how much Chakra is stored since she can store as much as she desires and use the ability whenever.

Check Tsunade's Strength of a Hundred Seal page.