Board Thread:Theories and Speculation/@comment-36225769-20180717143027/@comment-6769189-20180804202223

Chances are that using Izanagai after awakening the Rinnegan will blind an eye.

Mercuries96 wrote: No, izanagi doesnt blind you it close the eye for a period of time as shown with danzo's sharingan arm, having hashirama cells reduce that period of time, madara lived for a rly long period of time its 100% likly that over 30 years his eye is reopend(probebly WAY shorter then that as danzo was expecting his eyes to open the 2nd day since he have hashirama cells). izanami however blinds you(possably until the genjutsu is lifted(not specified but the genjutsu is never lifted in a lifetime of someone since itachi was removed before kabuto got free). Its permenant blindness. This was stated and shown in the series. The reason Danzo's arm Sharingan closed was so he could see how many more times he could use it. Hashirama cells extend the time it can be used for. Madara's eye was open after he used Izanagi and it was a blinded eye.