Board Thread:Theories and Speculation/@comment-32369776-20170708034118/@comment-734582-20170717105657

Rage gtx wrote: So only cite is non-canon novel and wike self reference? Well then I don't agree it's safe to conclude that they no longer exist. They were the founding clan, the most prominent and most powerful clan, yet in modern times there's no even the slightest mention. The fact that Naruto - an Uzumaki, not a Senju- was the next transmigrant against the trend suggests so. The Uchiha are considered the strongest clan, despite the fact that the Senju were canonically stronger suggests that they are gone.

The fact that there's so little mention of what happened to them suggests it wasn't considered a big deal, meaning that they probably disbanded. The fact that there's essentially no mention of modern-day senju despite being arguably THE most influential clan in the world suggests they're no longer around.