Board Thread:Naruto Discussions/@comment-7292165-20140718015350/@comment-2039297-20140719003328

If it's able-bodied Nagato vs. Minato, I really have no idea. Honestly, I still have a hard time believing anyone below a Juubi Jinchuriki can defeat a healthy, Part 2 Nagato single-handedly.

Anyway, Itachi would destroy Tsunade. I mean, he's way faster than her and has a Sharingan. These two together effectively nullify her skill in Taijutsu (especially considering Itachi's own skill in taijutsu). Throw in genjutsu and a perfect Susanoo; Done.

I think another interesting bout would be Minato vs. Itachi, but damn I have a hard time seeing either beat the other. I think Sage Mode and FTG might give Minato the advantage, since if he tags Itachi's body, it would render both Susanoo and the Yata Mirror useless, since he can simply instantaneously teleport inside them. And Sage Mode boosts Minato's already insane speed even higher.