Board Thread:Naruto Discussions/@comment-4271790-20141016102132/@comment-26302001-20141028200903

Tsunade was also 54 when when went into a coma.. she was well past her prime and expended almost all her chakra to save lives and save her own life too. Even with the 6 Paths Nagato was a monster so don't underestimate Tsunade, she survived the Chou Shinra Tensei and made sure that as much other people as possible could too. If she was not Uzumaki/Senju then I believe she would not have been able to do that