Amaterasu

Amaterasu, named after the Shinto Sun Goddess, is the highest level Fire Release technique, as well as one of the most powerful ninjutsu in existence. It is said to represent the, the antipode to Tsukuyomi, a genjutsu of similar power and a fellow Mangekyō Sharingan dōjutsu, said to represent the. Itachi Uchiha was the first person to be shown to be able to use Amaterasu. Sasuke later develops the ability after their fight.

The flames are summoned from the user's right eye and target anything within its field of vision. The flames will appear at the exact spot without moving, making it unavoidable as long as the user keeps his vision trained on the target. Itachi was easily able to catch Sasuke with the technique, though E was able to dodge at point-blank range with his Body Flicker Technique amplified by his Lightning Release Armor. The technique costs a large amount of chakra to utilize, and it causes the user's eye to bleed. It also is possible to implant the technique into another Sharingan user to have it activate at a certain point. Sasuke's mastery of the technique allows him to develop the Blaze Release element and use the flames as an additional shield in combination with Susanoo.

The jet-black flames of the Amaterasu are said to be as hot as the sun, they are described (by Zetsu) as the 'Most powerful Ninjutsu' after he talks about Tsukuyomi being the most powerful Genjutsu (during the Sasuke - Itatchi fight). They are capable of easily burning through the fire-resistant Summoning: Toad Mouth Bind and smothering regular fire. The amount of time it takes to burn a target is inconsistent, easily engulfing a forest and the Eight-Tailed Giant Ox in seconds, while taking a long time to burn various human targets. The flames are said to burn for seven days and seven nights, and cannot be extinguished with water or any other normal methods. The user can use their alternate eye to extinguish the flames, and the Fire Sealing Method was capable of removing the flames as well.

Influence
As from the ancient Japanese myth of Amaterasu, Tsukuyomi, and Susanoo, when Izanagi washed his face after escaping the underworld his left eye became the Sun Goddess, Amaterasu.