Board Thread:Consensus Track/@comment-38502514-20190216075013/@comment-34115-20190216102821

The problem with non-binary is that it is a real world term that is applied in the real world to normal human beings. Using the term to refer to Orochimaru – who originally identified as a cis-male and then made his gender nebulus because he essentially monsterified himself – risks being offensive by essentially comparing normal non-binary humans to essentially a monster.

So other/non-binary/fluid/etc are best reserved for any human characters in the series that identify with them. Assuming the manga/anime authors/staff were or ever will be forward thinking enough to actually incorporate characters with those traits non-offensively.