Izanagi and Izanami

is episode 338 of the Naruto: Shippūden anime.

Summary
With Izanami activated, and Kabuto trapped within its infinite loop, Sasuke uses this time to question his brother about the technique. Itachi tells Sasuke about the history behind Izanami's creation as well as the Uchiha clan use of the technique. Itachi ultimately reveals to Sasuke that Izanami was created with the sole purpose of stopping the users of the technique's counterpart: Izanagi so that they would accept their fate — which is also the way to escape the infinite loop. Angered by the fact that Itachi would cast a technique that has an escape route, Sasuke questions his motives to which Itachi says that he wished to give Kabuto an opportunity to accept his fate. Sasuke, however, claims that Itachi is perfect and rather different from Kabuto, however, the elder Uchiha refutes this claim. Elsewhere, Somewhere in a forest seemingly some distance away, a grown-up Urushi tells his comrade that he hoped by the time he gets home, Kabuto will be there. Back at the cave, Itachi prepares to put an end to the Impure World Reincarnation technique.

Trivia

 * In the preview of this episode, the flashback of the Uchiha inter-clan rivalry was shown in colour. However the episode shows the flashback in black and white in its airing.