Board Thread:Versus Debates/@comment-26943586-20150830195657/@comment-5547501-20150831085241

Madara spends prep time getting his other rinnegan. As soon as the battle begins he casts Infinte Tsukuyomi. GG.

Now, being serious, Itachi is not even a problem for either of the other two, due to both having Perfect Susano'o compared to Itachi's final Susano'o, as well as the fact the other two have better abilities. I'm not sure who would win between the other two. If it's EOS Sasuke, he might be able to dimension shift Madara (I haven't seen the Boruto movie so I don't know how this works, but if it's anything like Kaguya's, I don't think Madara could escape). On the other hand, Sasuke has shown next to no healing properties, having to rely on Karin/Jugo in all his fights where he got damaged. Madara as a Juubi-Jin is nearly invulnerable, as shown when he got blown and cut in half (both ways) and regenerated from both. Due to this extensive healing factor, I would say Madara wins.