Board Thread:Versus Debates/@comment-3523655-20180828232844/@comment-36921054-20180915160756

Even with Edo Tensei restricted, Kakazu has no method of dealing with Eight Branches. It is stronger than Manda, bigger than anything Kakazu has, can attack all five of Kakazu’s hearts simultaneously while the real Orochimaru destroys the isolated hearts with the element they are weak to, and it can regenerate whatever damage Kakazu causes.

I don’t think it is needed though. Orochimaru can tank a large number of Kakazu’s Jutsu without regenerating and regenerate whatever damage is done. Kakazu hasn’t shown anything that can put down Manda, and Orochimaru can use all five elements on his own. Orochimaru with Manda, fodder Snakes, clones, poisons, and regen should eventually win.

Orochimaru likely 10/10s this, because I don’t think Kakazu has any methods of actual victory, but I could be wrong. We never really got to see either character have an all out battle at full power.