Board Thread:Versus Debates/@comment-28300173-20160825054228/@comment-26537507-20160905151958

Orochimaru is not immortal. For most normal shinobi it would be almost impossible to kill him because they don't have enough power to force him to overuse his body replacement technique, however ninja like Naruto and Sasuke have enough power to kill him several times over. He's also susceptible to Sharingan genjutsu, which means they should have plenty of opportunities to take him out of the fight.