Board Thread:Boruto Discussions/@comment-38812954-20191003013630/@comment-9782468-20191003050909

If Madara survived extraction, he still would be only about as strong as Hashirama, who was weaker than mindless Juubito, who was weaker than regular Juubito, who was weaker than Juubidara, who was approximately on par with SPSM Naruto and Teen Rinnegan Sasuke (And they were messing him up pretty easy).

So no, he wouldn't stand a chance against and version of Momshiki or Isshiki.