Board Thread:Theories and Speculation/@comment-34656247-20180531072459/@comment-26107879-20180619002114

There is no evidence to suggest that Hashirama cannot be trapped by Tsukuyomi. You also cannot break out of a Mangekyo Sharingan Genjutsu like it's normal Genjutsu. If it were as easy as that, no one would be trapped by it except kids. Kakashi would have never even suffered a minute in the Genjutsu if all he had to do was use Chakra flow to break free. Once Itachi activates his Mangekyo, and someone makes eye contact, they are instantly caught in the Genjutsu. There hasn't been a single case where it's been shown otherwise. Once eye contact is made, it's done. But as for Hashirama ever being caught in it in the first place is entirely a different story.