Board Thread:Theories and Speculation/@comment-1872728-20160229033316/@comment-734582-20160308221028

MlGshinobi wrote: Konoha easily can solo bijuu though. Easily? no. Yamato only could control Kurama because of the necklace, and even so required considerable effort to do so.

Sharingan requires an expert user, it doesn't seem like any random uchiha can just go about controlling Biju. Else, Kakashi could've seen Kurama inside Naruto's mental space just like Sasuke. And even so, only a handful of people actually controlled Kurama as a free Biju, all people with the Mangekyou.

EDIT:

some findings and context:
 * other villages destroyed the Uzumaki. Who, and how many is never specified. It's possible that, as mentioned by others above, Konoha did in fact retaliate, destroyed those nations and absorbed them. Again, no mention is made of who exactly did it (Chapter 500).
 * It's also not mentioned in that chapter that the Uzumaki is a branch of anything, nor is it on the Wikipage. The Uzumaki are merely stated to be related to the Senju.

Thus, especially considering the latter, it's likely that the Uzumaki are related because they too descended from Ashura, as a different clan, and not as some Senju offshoot.