Board Thread:Consensus Track/@comment-38502514-20190216075013/@comment-3279282-20190219193130

Ninja Of War wrote:

Orochimaru inhabiting a foreign body with his soul and chakra doesn't change his biological sex. If it did, it would be stated so. Orochimaru's statement to Mitsuki can have a different meaning, as Mitsuki is a synthetic human. Again, assumptions are not facts.

Orochimaru entering a different body means Orochimaru has the sex of that body. It's not an assumption. He basically controls someone else's body from the inside. The entity that is Orochimaru has whatever sex its current host body has.