Board Thread:Theories and Speculation/@comment-28464629-20160515105435/@comment-734582-20160515131951

Madara, yes. Kaguya, no. Kaguya only absorbed the Shinju for more power.

That being said, Kakashi has the interesting achievement of being the person who got the closest to killing Kaguya, since he almost managed to Kamui the Gedo Statue.