Board Thread:Boruto Discussions/@comment-36351381-20180731025641/@comment-11813596-20180731085457

The Hyuga and Sarutobi don't fit with the Uzumaki and Uchiha. The Hyuga and Sarutobi and very much alive and well, compared to the other two which were hunted and is almost extinct.

Though if, for some reason, a full-blooded Senju would exist, I think Konoha would try to protect them (even if they're no Hashirama). But I don't think that they would have a huge impact to the story.