Board Thread:Theories and Speculation/@comment-45444155-20200826144850/@comment-32685487-20200826174006

Compatibility through DNA is needed. They are descendants of the Sage of Six Paths and somehow more direct than others are hence them surviving and their chakra and some physical traits changing. Another man ate Gyuki flesh and simply died, again the reason apparently being confirmed to be because of their lineage which Databook 4 confirms they are descendants of the Sage.