Board Thread:Theories and Speculation/@comment-45273751-20200322060033/@comment-32685487-20200407185528

Shikotsumyaku + 8 Gates + Sage Mode + Strength of a Hundred Technique, Strength of a Hundred would be constantly healing the damage that 8 gates would bring but the user would wear out faster. Sage Mode's sensing ability is another good advantage to it and Shikotsumyaku can strengthen the users bones like Kimimaro did to be able to resist even Gaara's sand. SO you got somebody who's speed and strength is insane, their body is insanely durable, and they have sensory abilities to boot. Along with close, mid, and long range techs. Kaguya can only be sealed to with SP: Chibaku Tensei to be defeated but in terms of strength, speed, and durability I think even she would fail to match this combo. While Naruto and Sasuke would lose without a single doubt in my mind.