Board Thread:Versus Debates/@comment-9782468-20150612024335/@comment-1751565-20150612120641

Tsunade wins for sure. she has wayyy more Chakra to last, and lets face it: She is as smart as he is to last the match. Taijutsu he cant risk cuz of her strength and medics, thus would resort to diversion/clone tactics- maintaining a distance, which we know wont work on a Sannin/Kage level ninja. If she uses her Seal or Summons Katsuyu, he has to resort to Mangekyo Sharingan, and what good would a kamui do. If by chance he does suck her in the dimension, she can always Reverse Summon herself back out using Katsuyu.

Also, alot of people forget that what the Chakra of the Hyakugaou Seal does is it activates your body and cells pumped with Enormous Chakra, increasing everything.