Board Thread:Naruto Discussions/@comment-25464204-20140925215818/@comment-25358381-20140926005158

Boonie98 wrote: 1. Is it possible that Hashirama could've been killed by Kakuzu. Kakuzu mentioned Hashirama being one of the first leaf shinobi that he ever fought.

Kakuzu had a mission to kill Hashirama but failed. He may have killed him afterwards to atone for his previous failure, but it is more likely that an entire army probably tried to take on Hashirama and he died in the ninja war.