Board Thread:Versus Debates/@comment-12098592-20160421053925/@comment-26104757-20160421083339

Tsunade's form of attack immediately puts her in a disadvantage. Having been so forward in collateral damage, it'll be difficult to measure a direct hit when Mei is able to produce currents of lava at her disposal fitted for mid/long range attacks. Mei can also play her trump card which would cause indefinite death. However, depending on the location — Mei's ability to shroud her surrounding in a corrosive mist is contemplated by the level of pH presented. Open fields would restrict the density needed to engulf Tsunade whereas close quarters can increase Mei's vapour to imminent toxicity; though, Tsunade's monstrous strength can easily break through solid barriers in order to escape and reform. Unfortunately for Mei, Tsunade's enormous chakra reserves along side medical utility grants her a healthy amount of time needed to tire and constrict Mei's pattern of combat in order to deliver a fatal blow.

With careful measures, quick thinking and the activation of her Byakugou; I think Tsunade is capable of defeating Mei. Mid/High difficulty, no doubt.