Manda II

is an enhanced clone that was created from Manda's cells and various drugs by Kabuto Yakushi.

Appearance
Manda II is even larger than the original, almost the same length as the Giant Island Turtle, making it one of the largest summons so far in the series. It also has four appendages similar to arms with four clawed fingers along with a cobra-like hood and a rattlesnake's tail. Manda II's teeth also take on the form of a poisonous snake's fangs, resembling those of a cobra while Manda's teeth took on the form of constrictor snake's teeth. He has the same dark markings over his eyes as the previous Manda.

In contrast to the original Manda, which was based more on a anaconda-like constrictor, Manda II has a mixture of features from many types of snakes and even oriental dragons.

Abilities
According to Kabuto Yakushi, this Manda is bigger, stronger, and has far more accurate senses than the original. Its massive strength was shown that, even in the water, it slowed down the Giant Island Turtle with ease, yanking it back. It was able to quickly kill the Giant Squid, leaving a giant bite mark on its head. Being a direct clone of the "strongest colossal serpent", it presumably possesses all of the original Manda's abilities, such as extreme speed and shedding its skin. It could also telepathically communicate with Kabuto.

Confining the Jinchūriki Arc
Summoned to seek out and restrain the Giant Island Turtle by Kabuto, it swam past and killed the Giant Squid which guards the island and latched onto the Giant Island Turtle's tail, immobilizing it for one of Deidara's bombs. It pulled the Giant Island Turtle as Deidara's bomb exploded which flipped it on its back rendering it incapacitated. It was later seen wrapping itself around the turtle's neck, contricting it. Eventually, with Yamato captured, Kabuto climbed into Manda II's nostril and the snake was de-summoned.