Missing-nin

are ninja who left their village, often because they have committed criminal acts. The ninja village that they are from try to track them down and eliminate them. Kirigakure has a special hunter-nin taskforce whose only objective is killing traitorous ninja. The ninja organization Akatsuki is composed of ten S-class missing-nin. Most of the missing-nin throughout the series are antagonists.

From Amegakure

 * Hisame
 * Kirisame
 * Murasame

From Iwagakure

 * Deidara (joined Akatsuki; deceased)

From Kirigakure

 * Zabuza Momochi (became an assassin-for-hire; deceased)
 * Demon Brothers - Gouzu and Meizu (joined Zabuza; presumed incarcerated)
 * Kisame Hoshigaki (joined Akatsuki)
 * Raiga Kurosuki (deceased)

From Konohagakure

 * Orochimaru (joined Akatsuki later created Otogakure; presumed deceased)
 * Sasuke Uchiha (joined Orochimaru; later joined Akatsuki)
 * Itachi Uchiha (joined Akatsuki; deceased)
 * Kabuto Yakushi (joined Orochimaru)
 * Yoroi Akado (joined Orochimaru; presumed deceased)
 * Misumi Tsurugi (joined Orochimaru; presumed deceased)
 * Madara Uchiha (created Akatsuki)
 * Aoi Rokusho (joined Amegakure; presumed deceased)

From Sunagakure

 * Sasori (joined Akatsuki; deceased)

From Takigakure

 * Suien (deceased)
 * Kakuzu (joined Akatsuki; deceased)

From Yugakure

 * Hidan (joined Akatsuki; presumed deceased)