Board Thread:Naruto Discussions/@comment-26636534-20180325094649/@comment-35103921-20180325143852

Itachis's girlfriend is mentioned in the manga, just not even by name. Someone comments that he killed his best friend, girlfriend and family to protect the village. I think it's in the last fight with Kabuto, or maybe when they revive the Hokages, but it's around that time.