Board Thread:Naruto Discussions/@comment-25124448-20140630200132/@comment-24200891-20140630202329

Kishimoto never confirmed if Hamura is the founder of the Hyuuga clan.

Uchiha clan was the most powerful before Itachi wiped it out. Hyuuga became the most powerful after that slaughter. Let me remind you that Neji HYUUGA had the best notes in his year and Sasuke UCHIHA had the best notes in his year, Hinata HYUUGA didn't beat him in notes. Also characteristic of Hyuuga is hand to hand combat boosted by chakra, when Uchiha are all fire users and learn very quickly thanks to their magical eyes. Sharingan copies techniques and reads moves of enemies and Byakugan detects weak points of enemies, I see predicting future as advantage over detecting weaknesses. The most powerful technique of Hyuuga are gentle fists lion steps and Uchiha have Susanno, which is summoning a giant spiritual warrior, small cats are nothing against giant warrior.

So my answer is Hyuuga are currently the most powerful clan of the Leaf, but master of Byakugan would lose against master of Sharingan.