Board Thread:Versus Debates/@comment-34656247-20180714075601/@comment-9782468-20180714173919

Sannin.

Itachi and Sasuke defeated Kabuto when they specifically weren't trying to kill him, and we know Itachi is Sannin level while Sasuke was approximately the same.

All they're abilities and experience together should grant them the win, especially since they have the advantage of teamwork.