Board Thread:Versus Debates/@comment-33959444-20180519003101/@comment-33308438-20180612103533

He would die in a weakened state.

He was physically injured and that, extremely heavily I believe. He was in great pain within his hideout and took extra medicines for recuperation purposes. His arms were in an erosion-like state which affected his body overall.

- Chakra reserves aren't a factor here. He has hax to make-up for his lack of reserves compared to Kisame.

- Kisame is fast in water, but Oro in his weakened state dodged 4 Tailed Kyuubi several times, and in his healthy state parried and overpowered Hiruzen who has got a 5 in Taijutsu. He can surely overpower him in CQC and not get caught by the Water Bubble due to his high evasion skills. Enma is also fast as it striked Kyuubi from Konoha and a weaker Hiruzen in Edo was capable of negating the Tree Branches of the God-Tree which was too fast for Naruto to run-away from. That show's the combined speed of Enma and Hiruzen which I believe is enough to catch Kisame. Hence Kusanagi can replicate the feat.

- Orochimaru has insane durability like Kisame plus he has Oral Rebirth to escape blunt force attacks from latter. Shadow Snake Hands make-up for Kisame getting too close to him for initiating CQC. I don't believe he could parry all the Blade Wielding Snakes with Samehada alone.

- Orochimaru was surprised when Kusanagi failed to pierce it, which mean's he never though it was incapable of piercing anything. He know's about Bijū-Chakra Cloak's from his experience, and being an Akatsuki Member. This part is headcanon but, I think it was Ashura's Soul which blocked the blade.