Board Thread:Theories and Speculation/@comment-32617252-20171101024222/@comment-6769189-20171102111714

Byakugo forces cell division. As humans our cells can only divide so many times. It basically shortens your lifespan depending how much it damage it heals.

How would Sakura not be able to control Sage Mode? She arguably has the best chakra control of her generation.

Minato and Jiraiya, other than skill, are average ninja amd one of them mastered Sage mode so having Raikage level durability is far from necessary.

Butterfly mightactually be the safest but the unhealthy eating habits needed to maintain it, you might get diabetes or heart disease lol