Izanagi and Izanami

is episode 338 of the Naruto: Shippūden anime.

Summary
With the Izanami activated and Kabuto trapped within its infinite loop, Sasuke uses this time and questions his brother about the technique. Itachi then tells Sasuke about the history of Izanami's creation as well as the Uchiha clan. Itachi ultimately reveals to Sasuke that Izanami was created with the sole purpose of stopping the users of the technique's counterpart — Izanagi so that they would accept their fate and reality — which is also the way to escape the infinite loop. Angered by this, Sasuke wonders why Itachi would cast a technique that has an escape route, to which Itachi says that he wished to give Kabuto an opportunity to accept his fate. Sasuke, however, claims that Itachi is perfect and rather different from Kabuto. The elder Uchiha seemingly refused this claim. Somewhere faraway in a forest, a grown-up Urushi tells his comrade that he hoped by the time he gets home, Kabuto will be there. Back at the cave, Itachi prepares to put an end to the Impure World Reincarnation technique.

Trivia

 * In the preview of this episode, the flashback of the Uchiha inter-clan rivalry was shown in colour. However the episode shows the flashback in black and white in its airing.