Board Thread:Naruto Discussions/@comment-26320097-20150423120614/@comment-1043414-20150701040204

Okay, I just had an interest theory. Factoring in both what was "confirmed" about Sakura being Sarada's mother and then the whole DNA test revealing a match to Karin, I came up with this. Keep in mind I am just guessing and accept whatever the truth is:

Sasuke and Sakura had Sarada together. Then at some point, baby Sarada got sick with a disease/illness not unlike what killed Itachi. Sasuke, not wanting to lose another loved one like that, went to Orochimaru for help. There, using a similar procedure that altered Yamato's DNA to match Hashirama's to obtain the First Hokage's powers, Orochimaru altered Sarada's DNA overlap Sakura's genetic make-up with Karin's. This thereby makes Sarada a match to Karin's DNA and giving Sarada the Uzumaki life-force and healing powers to save Sarada's life.

What do you think?