Board Thread:Theories and Speculation/@comment-25132842-20180312025951/@comment-734582-20180312100217

JamesDuh wrote: I think Asian's statement makes the most sense. Which would mean, that if both Itachi and Sasuke switched eyes, it would probably result in both obtaining EMS. To be clear, i do agree with that. We haven't seen that because MS users tend to be fairly self destructive and don't tend to live long enough to exchange eyes.

E.g. Shisui killed himself to give Itachi MS, Itachi died to give Sasuke MS, and EMS was unknown till Madara got it so it's not like Madara could've just switch eyes with Izuna. Well he could, he just didn't know it would've solved their problems much easier.