Jūgo of the Northern Hideout

is episode 117 of the Naruto: Shippūden anime.

Synopsis
While approaching the hideout, Karin explains that Jugo has abnormal homicidal impulses, and Jugo is the sole carrier of the enzyme necessary to create Orochimaru's Curse Mark. Upon arriving there, Sasuke and his team are attacked by a massive number of rampaging prisoners, who they manage to suppress. Later on, Sasuke is attacked by Jugo, but he expresses that he only wishes to talk with him. In the meantime, Naruto and Sakura find out that Sasuke has killed Orochimaru.