Board Thread:Versus Debates/@comment-27418151-20151224002611/@comment-26537507-20151225091224

Don't underestimate Kisame though. We're talking about a ninja whose 30% clone can beat Might Guy in hand-to-hand combat, and who also has enough durability to: 1) survive Daytime Tiger and 2) then proceed to resist interrogation and break out of Yamato's wooden stocks. It was also Kisame that pressured Killer Bee, a perfect Jinchuriki, to the point where he was literally toying with him.

All that being said, I still think Kakashi would win thanks to his versatility and intelligence, but it definitely wouldn't be easy.