Board Thread:Versus Debates/@comment-45235418-20200316185119/@comment-4080775-20200322171436

If anything, Minato has the advantage, not Itachi. Minato's speed is more than enough to blitz Itachi. Some of Minato's kunai may get blocked but that won't matter because if Minato runs circles around Itachi and throw Kunai directly at him and above him, Minato can teleport to any of these Kunai mid flight and literally put himself in various blind spots, leaving Itachi open to attack. Minato can then Rasengan him from there. If Itachi resorts to Susanoo, Minato could mark it and teleport it away, likely every time he manifests it without needing to remark it.

All it takes is for Minato make physical contact or remotely control the seal to mark Itachi and it will be pretty much good game from there. Also, if Edo Tensei are immune to Infinite Tsukuyomi, what's to say they aren't immune to the inferior Tsukuyomi?

Even if Minato gets stabbed, he could just teleport to one of his Kunai elsewhere and literally heal from the damage. The sword can't seal him fast enough to keep him from teleporting to a new area.

Regardless if he enters Sage Mode or not, he has access to Negative Emotions Sensing and can use it to sense evil intent coming from Itachi and his attacks.