Board Thread:Theories and Speculation/@comment-32617252-20170724023202/@comment-734582-20170724123205

Elveonora wrote: I'm sure chakra affects DNA in some cases, but it seems complicated and unexplained. Kurama might have affected Naruto's genes somehow, but it seems very minor, it's not like he has fox genes. Some chakra affects DNA. The confusion is mostly because Manga and Anime use the word "chakra" for very different things. IE Biju chakra can do anything from being mere chakra to granting people their powers as if it was their own.

Practically however, we can see with both Gaara and edo Nagato that if one holds borrowed power for long enough, it 'counts' as their own. So since Naruto has had Kurama's chakra since birth, at least some of that power is considered "his". Meaning that you could extract Kurama's power from Naruto's flesh.

I don't think it's necessary that it changes his DNA though.