Board Thread:Boruto Discussions/@comment-33545035-20191020164526/@comment-1411686-20191027073355

im thinking Isshiki is going to be a rogue Otsutsuki clan member. He arrived on Earth but he presumably has been chillin as Jigen a human and likely not made contact with the main clan. I think he won't be the final villain IMO. The manga still needs to address the Jogan, and we have yet to see Toneri or Urashiki in the manga so i think once this Jigen mess gets solved, the next arc will have more main family clan members like Urashiki and will involve Toneri.

You can say Urashiki is anime only, but i seriously doubt it. He was created by Kishimoto and reused for the anime, but if he was just gonna be a throwaway character they would have killed him off in the Chunin Exams arc. Sumire who is far less important than a whole ass Otsutsuki member was brought into the manga from the anime, so im sure he will too. They pretty much have stated alot of the stuff in the anime will be used to flesh out content in the manga, so im sure that will apply to Urashiki appearing earlier in the anime before he debuts in the manga.

Plus he can't really die in the anime now, otherwise someone will get Kama. And if you look closely, the third pair on the Otsutsuki clan mural in ch 35, you can barely make out the top one resembling Urashikis horn.

https://imgur.com/a/l4hNQqz