Board Thread:Theories and Speculation/@comment-31099706-20170327120301/@comment-26773508-20170327171946

@Thekillman and @Ravenlot: Indeed, it seems that Sasuke's previous two encounters might have something to do with the perceived lack of time manipulation. And I was thinking about Tsukuyomi a few hours ago, and its hypothetical effectiveness against someone like EMS Madara. So Itachi fans have been arguing that even if Madara were to break free from Tsukuyomi within a fraction of a second, his mind would still be shattered since one second in Tsukuyomi in real-time can be equivalent to hours or days or even years in Tsukuyomi-time. But as @Ravenlot pointed out, this argument could be a fallacy since what seems to matter the most for breaking out of Tsukuyomi is Tsukuyomi-time itself, NOT real-time. If this is true, then it nullifies Itachi's alleged one-shot against EMS Madara.

Perhaps we can look at it with more clarity by looking at the biological processes going on inside the victim's physical brain while s/he is trapped inside Tsukuyomi. In order for the victim to perceive days or years inside Tsukuyomi, the synapses between neurons must exchange electric signals with each other extremely rapidly, within very very small fractions of a second (say, less than a nanosecond for the sake of argument).

This is because neurons in different parts of the brain MUST fire and communicate with each other in order for perception to take place. That means Tsukuyomi has a limit when it comes to time manipulation, and that limit is directly proportional to the maximum speed at which electric signals can travel between two synapses.

In other words, what the victim does in Tsukuyomi-time will have direct bearing in real-time, since the brain itself is processing information at the rates of fractions of a second. If the victim reacts and breaks out of the jutsu within, say, a minute of Tsukuyomi-time, then in real-time, he breaks out within a nanosecond. And in real-time, to other observers, it would seem as though the Tsukuyomi wasn't even cast at all.

So contrary to the claims of Itachi fans, it is possible for EMS Madara to break out of Tsukuyomi in nanoseconds or microseconds in real time. Their entire argument revolves around Madara not being able to break out of Tsukuyomi in a time-span lesser than one second. But this might not be true after all, because neurons must communicate with each other at less than a millionth of a second for Madara to perceive Tsukuyomi-time. And if Madara's brain can communicate that fast to create the illusion of Tsukuyomi-time, then surely the neurons in his brain can react as quickly to break Tsukuyomi, thus sparing him days and months worth of torture.

I just hope my ramblings above make some sense, though.