Board Thread:Theories and Speculation/@comment-31099706-20170327120301/@comment-7292165-20170423050856

It doesn't matter. Sakura thought it was real and passed out. But, if you want something pain related, how about Orochimaru believing to be pierced by several stakes, and that was on Genjutsu: Sharingan. Proving that the Tsukuyomi proves no different when convincing the brain that they are in pain.