He invaded the village, killed the third, wanted to possess Sasuke's body, did several genetic experiments, joined a criminal organization aimed at dominating the world & was still invited to Naruto's wedding.
Used his own student as a test subject in experiments that threatened her life
Kidnapped hundreds of children experimented on them used them as his backup bodies and had them fight to death just to use the surviving ones in experiments and use them as disposable pawns until their death