As Frieza's henchmen, I would have access to advanced level technology that we may not see in centuries and traverse space and see countless different forms of life. Also, I'd probably never even see Frieza due to how low on the chain of command I'd be (there are probably hundreds of thousands of Frieza Force members) so that's another upside.
With Orochimaru... Well, I'd probably just die from having a curse mark imprinted on me and failing to adapt to it. That, or I'd get experimented on until I'm either insane or dead. There aren't enough people under Orochimaru's command that would help me be under the radar so I'm always potentially on the chopping block.