To my knowledge, no. To get it, yes. And to use it fully, yes. But not to manifest a severely weakened form of it.

Just asking because sasuke has lost his rinnegan which also hold his second have his mangekyo sharigan

To my understanding, he should still be capable of activating it, if at half power. Itachi, without his eyes, was able to manifest a weaker version of his.

No, but for Perfect Susanoo, you need at least one rinnegan.

^that's not true

Forgot about Kakashi.

He's not the only one, Sasuke and Madara also had Perfect Susanoo with just EMS

Its been years since i've watched the show and the last time as well.

Ma gelato is all that’s needed for Susanoo’s initial activation. All the forms are pure training. It’s just that EMS and Rinnegan users were the only ones to posses their eyesight and visual prowess for long enough to reach that state.