Narutoverse because of hax:

(Kamui, izanagi, kotoamatsukami, infinite tsukoyomi, etc)

Hate to break it to you but cosmic garou can literally destroy universes everyone's dead by the time they find out they're even fighting someone

By the time madara tries to unleash his rinnesharingan, garou would have killed him

Yes

Itachi uses his genjutsu and Kakashi kamuis his head off

Garou will just dodge kakashi’s kamui. Also garou has no chakra

Izanagi could still work

Photo is misleading thought it was monster garou

Izangi won’t work garou will just kill them again

But how effective would izanagi be? It’s not like bringing back dead characters will do any good if he just kills them again.