Kakuzu may be stronger than Sasori, but not Tobirama. In the battle with Kakashi's squad, Kakuzu turns out to be such an old grandfather that he spent a long time tinkering with Naruto's clones, trying to figure out where the real one was. Kakuzu also has weak sensory abilities, and Kakashi and Naruto stabbed him twice in the back. But, after 2 blows from Naruto, Grandpa Kakuzu couldn't stand it and went to heaven. Tobirama can just create 50-100 clones, and Kakuzu's brain can't stand the overheating to figure out where the real one is. At this time, one or more of Tobirama's clones use the death god technique, and Kakuzu's soul is simply sealed, which he will do in order not to mess with the 4 hearts. The only hope is that old grandpa's hearts are trying to catch up with Tobirama and kill him. But it won't last long, as Rama just teleports away from their destructive techniques and the battlefield. And anyway, the fight will end with Kakuzu going to a nursing home.

Children's tales of Izuna kicking Tobirama and the 2nd Hokage becoming a statistic are not accepted. Since Tobirama, with the exception of his only brother and the one who was not from the Uchiha clan, was able to kill and humiliate an Uchiha (Izuna) with the MANGEKYŌ Sharingan, as a statistic or a genin. While Kakuzu couldn't even handle the genin Naruto, who did not have mods with Kurama. And Tobirama tried to fight 2 half-bijuu.
You can attach to infinity a gif image of Madara Uchiha , stuffed with all the doping from anime Naruto, piercing Tobirama with black rods, but to seriously claim that the 2nd Hokage is weaker than almost all Naruto characters is stupid
I'm keeping quiet about Hashirama because Kakuzu will become a boxing scarecrow for him.