#1 Orochimaru (Boruto)
This one kind of is a no brainer obviously he’s a lot stronger in Boruto, still immortal and is more skilled and knows more forbidden jutsu. In the novels he’s as skilled as base Naruto. And If you think Amado is a mad scientist Orochimaru is more dangerous and on another level
#2 Orochimaru (Part 1) (Edo Tensei)
With Orochimaru at full power with both arms and Edo tensei in his arsenal he became incredibly strong, he could take down kage level ninja like the kazekage Rasa and he could take on the 3rd Hokage who was one the strongest ninja in history even at his old age. He was also able to fight two other sanin with no arms. And hold back the 9 tails (4 tail Naruto)
#3 Jiraiya (Sage Mode)
Jiraiya was incredibly strong in this mode taking down 3 paths of pain is not easy especially without intel. And his wide arrange of Jutsu and senjutsu attacks on top of sound genjutsu wirg ma and pa on his shoulders he’s a force to be reckoned with
#4 Tsunade (Hundred Healings)
She can regenerate organs and limbs in this mode and has an incredible chakra boost. Since this is the same Jutsu used by Sakura we can compare them, Sakura had chakra comparable to 1/4 of the amount SPSM Naruto has according to Obito. And tsunade has more chakra as she uses extra chakra to alter her appearance 24/7. She should also be able to take hits from truth seeking orbs like Sakura. She has insane strength and AP and lifting strength. This Jutsu is so powerful because it dates back to the time of the Sage of six paths
#5 All Sanin in Base at Full Power
Jiraiya is stated to be on par with Part 1 Orochimaru in the databooks. (Probably minus Edo tensei) And in my opinion Tsunade is relative at full power as well. So I’m going to say they all should be equal or relative to each other. During the 3 way deadlock when they fought each other they were at half power either drugged, no arms or a mental nerf (ptsd)