Madara = Kaguya Otsutuski's vessel
Jigen= Isshiki Otsutsuki's vessel
Which vessel is more more powerful? Madara, who has inherited Kaguya's powers or Jigen, who has inherited Isshiki's powers?
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If we go with the capabilities of Jigen currently shown in the manga, then Madara would surely win by outlasting him since Jigen's body would crack shortly after he overuses Isshiki's power.
(Edited by Ravenlot 27)