"Itachi's Question!!" (イタチの問い!!, Itachi no Toi!!) is chapter 549 of the original Naruto manga.
Nagato talks to Naruto about how his expression has changed since their last meeting. Naruto says he was able to conquer his hatred because of his parents, B, and Nagato's teachings of pain. Itachi tells Naruto that he wants to ask him a question, and Naruto says the same. Meanwhile, Kabuto is glad that he has found the Eight-Tails and Nine-Tails first and wonders what Tobi's reaction will be. Kabuto commands them to attack. Itachi attacks with a fireball, B cuts it in half with his Samehada. Itachi begins to fight with Naruto, and B. As they fight Itachi asks Naruto about Sasuke. Naruto tells him about Sasuke's desire to destroy Konoha and that Tobi told him about Itachi's secret mission. Itachi asks Naruto to keep his mission a secret as he wants the Uchiha name to keep its reputation. Nagato pulls Naruto and a rock from the nearby lake in a head-on collision, but Naruto dodges it. Nagato summons two creatures. Naruto attacks the dog as it multiplied. Itachi and B fight each other. Itachi jumps on to Nagato's bird and activates his Mangekyō Sharingan. A crow emerges from Naruto's mouth.